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Peter B. Dervan

Peter B. Dervan

Bren Professor of Chemistry, Emeritus

B.S., Boston College, 1967; Ph.D., Yale University, 1972; Assistant Professor, Caltech, 1973-79; Associate Professor, 1979-82; Professor, 1982-88; Bren Professor, 1988-. Chair, Division of Chemistry and Chemical Engineering, 1994-99.
Phone: 626-395-6002
Office: Crellin Laboratory 351
Mail Code: MC 164-30 CR
Research Summary
Organic, Physical Organic, and Chemical Biology
Profile

Assistant: Victoria Brennan

Professor Dervan's research program addresses a wide range of fundamental problems at the interface of organic chemistry and biology. Elucidating the chemical principles for the molecular recognition of DNA by small molecules and their use in biology, in particular gene modulation and DNA detection, are unifying themes.

Publications

For a complete publications list, see feeds.library.caltech.edu


Finn, Paul B.; Bhimsaria, Devesh et al. (2020) Single position substitution of hairpin pyrrole-imidazole polyamides imparts distinct DNA-binding profiles across the human genome

Kurmis, Alexis A.; Dervan, Peter B. (2019) Sequence specific suppression of androgen receptor–DNA binding in vivo by a Py-Im polyamide

Dervan, Peter B. (2019) A Personal Perspective on Chemical Biology: Before the Beginning

Diaz-Perez, Silvia; Kane, Nathanael et al. (2018) Interference with DNA repair after ionizing radiation by a pyrrole-imidazole polyamide

Dervan, Peter B.; Kurmis, Alexis A. et al. (2018) Molecular Recognition of DNA by Py–Im Polyamides: From Discovery to Oncology In: DNA-targeting Molecules as Therapeutic Agents