CB & MB Faculty

Research Areas
Approaches and Techniques

Genome integrity and Expression
Campbell, Chong, Semlow

Proteome integrity, function, and organization
Chong, Clemons, Hoelz, Hsieh-Wilson, Shan

Membrane Biology
Clemons, Shan, Rees, Hoelz

Post-translational modifications and cellular signaling
Chong, Clemons, Hoelz, Hsieh-Wilson, Shan

Protein engineering and molecular medicine
Arnold, Clemons, Hoelz, Hsieh-Wilson, Mayo, Shan, Shapiro, Wei

Structural Biology
Clemons, Hoelz, Shan, Rees

Single molecule Biophysics
Chong, Shan, Wei

Molecular Cell Biology
Campbell, Chong, Hoelz, Semlow

Chemical Probes for Biological discovery
Clemons, Hsieh-Wilson, Wei

Computation
Clemons, Goddard, Mayo

Frances H. Arnold

Linus Pauling Professor of Chemical Engineering, Bioengineering and Biochemistry; Director, Donna and Benjamin M. Rosen Bioengineering Center

Biocatalysis, protein engineering, enzyme evolution, synthetic biology

Research Website

Judith L. Campbell

Professor of Chemistry and Biology

DNA replication in the yeast Saccharomyces cerevisiae dynamics in signaling transductions and exploring biological interactions in single cells

Research Website

Shasha Chong

Assistant Professor of Chemistry; Ronald and JoAnne Willens Scholar

Transcription; intrinsically disordered regions; single-molecule imaging and biophysics; cancer biology

Research Website

William M. (Bil) Clemons, Jr.

Arthur and Marian Hanisch Memorial Professor of Biochemistry

Membrane protein structure; protein synthesis and translocation; X-ray crystallography

Research Website

William A. Goddard

Charles and Mary Ferkel Professor of Chemistry, Materials Science, and Applied Physics

Quantum chemistry, molecular dynamics, statistical physics: simulation and design of biological, polymer, ceramic, and metal systems; Reaction mechanisms in homogeneous and heterogeneous catalysis; Prediction of Protein Structure and Function; Nanotechnology, bionanotechnology

Research Website

André Hoelz

Mary and Charles Ferkel Professor of Chemistry and Biochemistry

Structure-function studies of the nuclear pore complex and the histone-modifying machinery; X-ray crystallography

Research Website

Linda C. Hsieh-Wilson

Milton and Rosalind Chang Professor of Chemistry

Synthetic and combinatorial chemistry; neurobiology; protein structure and function

Research Website

Rustem F. Ismagilov

Ethel Wilson Bowles and Robert Bowles Professor of Chemistry and Chemical Engineering; Merkin Institute Professor; Director of the Jacobs Institute for Molecular Engineering for Medicine

Global Health; Microbial communities and biophysics of the gut microbiome; Diagnostics and antimicrobial susceptibility testing; Microfluidics and single molecule and single cell analysis; Complex Networks of reactions, cells and organisms

Research Website

Stephen L. Mayo

Bren Professor of Biology and Chemistry; Merkin Institute Professor

Protein design, structure, and stability; computer simulation techniques

Research Website

Carl S. Parker

Professor of Biochemistry

Molecular Mechanisms controlling gene expression

Research Website

Douglas C. (Doug) Rees

Roscoe Gilkey Dickinson Professor of Chemistry; Investigator, Howard Hughes Medical Institute

Protein Structure and Energetics; X-ray Crystallography

Research Website

Daniel Semlow

Assistant Professor of Biochemistry; Ronald and JoAnne Willens Scholar

DNA replication and repair; nucleic acid chemistry

Research Website

Shu-ou Shan

Altair Professor of Chemistry; Executive Officer for Biochemistry and Molecular Biophysics

Molecular machines in protein folding, targeting, and quality control; mechanism and engineering of molecular chaperones

Research Website

Mikhail G. Shapiro

Max Delbrück Professor of Chemical Engineering and Medical Engineering; Investigator, Howard Hughes Medical Institute; Director, Center for Molecular and Cellular Medicine

Molecular and cellular engineering; Non-invasive imaging and control of biological function; Cell and gene therapy; Neuroscience; Cancer; Nanotechnology; Synthetic biology

Research Website

Lu Wei

Assistant Professor of Chemistry; Investigator, Heritage Medical Research Institute

Optical spectroscopy and microscopy, Biophysics, Bio-imaging, Chemical probe development.

Research Website