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Organic Chemistry Seminar

Monday, May 4, 2015
4:00pm to 5:00pm
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Noyes 147 (J. Holmes Sturdivant Lecture Hall)
The Design, Discovery, and Applications of Catalytic Reactions Involving C-C, C-O, or C-N Bond Activation
Christopher J. Douglas, Assistant Professor of Chemistry, Department of Chemistry, University of Minnesota-Twin Cities,

Developing catalysis based on the activation of traditionally challenging bonds is an active area of research in organometallic and organic chemistry. New bond activation chemistry could change the way synthetic chemists approach the construction of complex molecules by allowing non-traditional retrosynthetic disconnections to be made.  This presentation will focus on recent developments at Minnesota in the activation and functionalization of unstrained bonds adjacent to carbonyls.  Catalytic reactions are designed with an eye towards complexity-building reactions.  For example, group 9 or 10 metal-mediated activation of the C-C bond of ketones, the C-O bond esters, or the N-CN bond of cyanamides enables carboacylation, oxyacylation, and aminocyanation processes of alkenes, respectively.  Our contributions to these processes will be presented.

For more information, please contact Lynne Martinez by phone at 626-395-4004 or by email at [email protected].