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Special Organic Chemistry Seminar - Organic Syntheses Lecture

Wednesday, March 22, 2023
4:00pm to 5:00pm
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Gates Annex B122
New Directions in Nickel Catalysis
Abigail Doyle, Professor, Department of Chemistry, University of California Los Angeles,

Zoom available upon request. Sponsored by Organic Syntheses

Whereas recent advances in the field of Pd-catalyzed cross coupling have been driven largely by ligand and precatalyst design,  coupled to insights into reaction mechanism, related studies for Ni have received less attention. For example, modern ligand frameworks designed for Pd and other precious metal catalysts (Rh, Ir) have been largely unsuccessful when applied to Ni. To address these needs, the Doyle lab has developed novel ligand classes and precatalysts for Ni and demonstrated that they enable new methodologies not previously possible with existing frameworks. Furthermore, our lab has sought to uncover the mechanistic basis for reactivity in a variety of Ni-catalyzed cross-coupling reactions through inorganic synthesis, kinetic analysis, computational studies, statistical modeling, and ultrafast and steady-state spectroscopy. This lecture will describe our recent efforts in these directions.

For more information, please contact Annette Luymes by phone at x6016 or by email at [email protected].