Organic Chemistry Seminar

The field of Synthetic Immunology aims to develop synthetic systems capable of controlling and/or creating immunological function. This talk will focus on our laboratory s research efforts in this area, including ongoing progress toward antibody-recruiting molecules, a class of bifunctional agents capable of interacting with antibodies already present in the human bloodstream and enhancing immune recognition of cancer cells and virus particles; technologies for re-engineering the cell wall of Gram-positive bacteria with non-native molecules for application in vaccine development; and the chemical synthesis of a class of natural ligands believed to be involved in triggering innate immune responses. Overall, these strategies have the potential to enable wide-ranging advances in both basic and clinical science.