Assistant: Sadie Rubalcava
In the Barton group, we have examined the chemical and physical properties of DNA and the biological implications of those properties. Our research has shown that DNA is more than just the library of the cell, existing only to hold genetic information; on the contrary, DNA is a molecule rich in chemical complexity and full of surprises.
Previously, the Barton group has shown that the overlapping π system of stacked DNA bases can mediate the transfer of electrical charge (electrons and holes) over long distances. This DNA-mediated charge transfer (DNA CT) occurs in a variety of sequence contexts and between various types of charge donors and acceptors, shows a shallow distance dependence, and is exquisitely sensitive to perturbations to the base stack such as chemical damage and base pair mismatches. Nature utilizes this chemistry for long range signaling between proteins containing 4Fe4S clusters in replication and repair.
Our current research was focused in three areas:
- Using the unique binding environment of DNA to develop specific probes for DNA mismatches and lesions
- Examining the biological implications of DNA CT
- Designing electrochemical devices which can be used to sense DNA damage or report on DNA and protein binding events.
Publications
Saunders, Scott H.; Tse, Edmund C. M. et al. (2020) Extracellular DNA Promotes Efficient Extracellular Electron Transfer by Pyocyanin in Pseudomonas aeruginosa Biofilms Cell; Vol. 182; No. 4; https://resolver.caltech.edu/CaltechAUTHORS:20191213-144717393
Threatt, Stephanie D.; Synold, Timothy W. et al. (2020) In vivo anticancer activity of a rhodium metalloinsertor in the HCT116 xenograft tumor model Proceedings of the National Academy of Sciences of the United States of America; Vol. 117; No. 30; https://resolver.caltech.edu/CaltechAUTHORS:20200714-092121048
Silva, Rebekah M. B.; Grodick, Michael A. et al. (2020) UvrC Coordinates an O₂-Sensitive [4Fe4S] Cofactor Journal of the American Chemical Society; Vol. 142; No. 25; https://resolver.caltech.edu/CaltechAUTHORS:20200615-113627458
Nano, Adela; Bailis, Julie M. et al. (2020) Cell-Selective Cytotoxicity of a Fluorescent Rhodium Metalloinsertor Conjugate Results from Irreversible DNA Damage at Base Pair Mismatches Biochemistry; Vol. 59; No. 5; https://resolver.caltech.edu/CaltechAUTHORS:20200122-124618192
Barton, Jacqueline K.; Silva, Rebekah M. B. et al. (2019) Redox Chemistry in the Genome: Emergence of the [4Fe4S] Cofactor in Repair and Replication Annual Review of Biochemistry; Vol. 88; https://resolver.caltech.edu/CaltechAUTHORS:20190624-083057369
Boyle, Kelsey M.; Nano, Adela et al. (2019) Cellular Target of a Rhodium Metalloinsertor is the DNA Base Pair Mismatch Chemistry: a European Journal; Vol. 25; No. 12; https://resolver.caltech.edu/CaltechAUTHORS:20190114-083314706
Tse, Edmund C. M.; Zwang, Theodore J. et al. (2019) Effective Distance for DNA-Mediated Charge Transport between Repair Proteins ACS Central Science; Vol. 5; No. 1; https://resolver.caltech.edu/CaltechAUTHORS:20190111-103734017
O'Brien, Elizabeth; Salay, Lauren E. et al. (2018) Yeast require redox switching in DNA primase Proceedings of the National Academy of Sciences of the United States of America; Vol. 115; No. 52; https://resolver.caltech.edu/CaltechAUTHORS:20181213-083058525
O'Brien, Elizabeth; Holt, Marilyn E. et al. (2018) Substrate Binding Regulates Redox Signaling in Human DNA Primase Journal of the American Chemical Society; Vol. 140; No. 49; https://resolver.caltech.edu/CaltechAUTHORS:20181115-142248448
Holt, Marilyn E.; Salay, Lauren E. et al. (2018) Functional and structural similarity of human DNA primase [4Fe4S] cluster domain constructs PLoS ONE; Vol. 13; No. 12; https://resolver.caltech.edu/CaltechAUTHORS:20190102-135257451
Ekanger, Levi A.; Oyala, Paul H. et al. (2018) Nitric Oxide Modulates Endonuclease III Redox Activity by a 800 mV Negative Shift upon [Fe_4S_4] Cluster Nitrosylation Journal of the American Chemical Society; Vol. 140; No. 37; https://resolver.caltech.edu/CaltechAUTHORS:20180827-094622072
McDonnell, Kevin J.; Chemler, Joseph A. et al. (2018) A human MUTYH variant linking colonic polyposis to redox degradation of the [4Fe4S]²⁺ cluster Nature Chemistry; Vol. 10; No. 8; https://resolver.caltech.edu/CaltechAUTHORS:20180222-102406884
Zwang, Theodore J.; Tse, Edmund C. M. et al. (2018) Sensing DNA through DNA Charge Transport ACS Chemical Biology; Vol. 13; No. 7; https://resolver.caltech.edu/CaltechAUTHORS:20180524-092613150
Boyle, Kelsey M.; Barton, Jacqueline K. (2018) A Family of Rhodium Complexes with Selective Toxicity towards Mismatch Repair-Deficient Cancers Journal of the American Chemical Society; Vol. 140; No. 16; https://resolver.caltech.edu/CaltechAUTHORS:20180405-142009074
Zwang, Theodore J.; Tse, Edmund C. M. et al. (2018) A Compass at Weak Magnetic Fields Using Thymine Dimer Repair ACS Central Science; Vol. 4; No. 3; https://resolver.caltech.edu/CaltechAUTHORS:20180312-100907248
Saunders, Scott H.; Yates, Matthew D. et al. (2018) Probing Phenazine Electron Transfer and Retention in Pseudomonas Aeruginosa Biofilms Biophysical Journal; Vol. 114; No. 3; In: 62nd Annual Meeting of the Biophysical-Society, 17-21 February 2018, San Francisco, CA https://resolver.caltech.edu/CaltechAUTHORS:20180510-091834521
Bartels, Phillip L.; Stodola, Joseph L. et al. (2017) A Redox Role for the [4Fe4S] Cluster of Yeast DNA Polymerase δ Journal of the American Chemical Society; Vol. 139; No. 50; https://resolver.caltech.edu/CaltechAUTHORS:20171211-090046935
Nano, Adela; Boynton, Adam N. et al. (2017) A rhodium-cyanine fluorescent probe: detection and signaling of mismatches in DNA Journal of the American Chemical Society; Vol. 139; No. 48; https://resolver.caltech.edu/CaltechAUTHORS:20171115-104208193
Chazin, Walter; Barton, Jacqueline et al. (2017) The Mechanisms for counting and handoff by human DNA primase: a role for the 4Fe-4S cluster? Protein Science; Vol. 26; No. S1; In: 31st Annual Symposium of the Protein-Society, 24-27 July 2017, Montreal, Canada https://resolver.caltech.edu/CaltechAUTHORS:20180112-074331185
Tse, Edmund C. M.; Zwang, Theodore J. et al. (2017) The Oxidation State of [4Fe4S] Clusters Modulates the DNA-Binding Affinity of DNA Repair Proteins Journal of the American Chemical Society; Vol. 139; No. 36; https://resolver.caltech.edu/CaltechAUTHORS:20170818-103108794
Ha, Yang; Arnold, Anna R. et al. (2017) Sulfur K-Edge XAS Studies of the Effect of DNA Binding on the [Fe_4S_4] Site in EndoIII and MutY Journal of the American Chemical Society; Vol. 139; No. 33; https://resolver.caltech.edu/CaltechAUTHORS:20170719-101916396
O'Brien, Elizabeth; Holt, Marilyn E. et al. (2017) Response to Comments on "The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport" Science; Vol. 357; No. 6348; https://resolver.caltech.edu/CaltechAUTHORS:20170720-130038340
Boynton, Adam N.; Marcélis, Lionel et al. (2017) A Ruthenium(II) Complex as a Luminescent Probe for DNA Mismatches and Abasic Sites Inorganic Chemistry; Vol. 56; No. 14; https://resolver.caltech.edu/CaltechAUTHORS:20170705-085833705
Bailis, Julie M.; Weidmann, Alyson G. et al. (2017) Rhodium metalloinsertor binding generates a lesion with selective cytotoxicity for mismatch repair-deficient cells Proceedings of the National Academy of Sciences of the United States of America; Vol. 114; No. 27; https://resolver.caltech.edu/CaltechAUTHORS:20170622-100942401
Bartels, Phillip L.; Zhou, Andy et al. (2017) Electrochemistry of the [4Fe4S] Cluster in Base Excision Repair Proteins: Tuning the Redox Potential with DNA Langmuir; Vol. 33; No. 10; https://resolver.caltech.edu/CaltechAUTHORS:20170306-132005349
O'Brien, Elizabeth; Holt, Marilyn E. et al. (2017) The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport Science; Vol. 355; No. 6327; https://resolver.caltech.edu/CaltechAUTHORS:20170223-150518455
Barton, Jacqueline K. (2016) Ahmed H. Zewail Chemical & Engineering News; Vol. 94; No. 49; https://resolver.caltech.edu/CaltechAUTHORS:20170112-075221809
Zwang, Theodore J.; Hürlimann, Sylvia et al. (2016) Helix-dependent Spin Filtering through the DNA Duplex Journal of the American Chemical Society; Vol. 138; No. 48; https://resolver.caltech.edu/CaltechAUTHORS:20161117-080611089
Boyle, Kelsey M.; Barton, Jacqueline K. (2016) Targeting DNA mismatches with rhodium metalloinsertors Inorganica Chimica Acta; Vol. 452; https://resolver.caltech.edu/CaltechAUTHORS:20160125-103800513
O'Brien, Elizabeth; Silva, Rebekah M. B. et al. (2016) Redox Signaling through DNA Israel Journal of Chemistry; Vol. 56; No. 9-10; https://resolver.caltech.edu/CaltechAUTHORS:20161128-100708366
Arnold, Anna R.; Zhou, Andy et al. (2016) Characterization of the DNA-Mediated Oxidation of Dps, A Bacterial Ferritin Journal of the American Chemical Society; Vol. 138; No. 35; https://resolver.caltech.edu/CaltechAUTHORS:20160907-083741647
Boynton, Adam N.; Marcélis, Lionel et al. (2016) [Ru(Me_4phen)_2dppz]^(2+), a Light Switch for DNA Mismatches Journal of the American Chemical Society; Vol. 138; No. 15; https://resolver.caltech.edu/CaltechAUTHORS:20160418-100658436
Holt, Marilyn E.; O'Brien, Elizabeth et al. (2016) Cracking Open a Molecular Calculator: DNA Charge Transport and Primase Biophysical Journal; Vol. 110; No. 3; In: 60th Annual Meeting of the Biophysical-Society, February 27-March 2, 2016, Los Angeles, CA https://resolver.caltech.edu/CaltechAUTHORS:20160603-153447332
Silva, Rebekah M. B.; Zhou, Andy et al. (2016) DNA-Mediated Redox Signaling in Bacterial Nucleotide Excision Repair by UvrC Biophysical Journal; Vol. 110; No. 3; In: 60th Annual Meeting of the Biophysical-Society, February 27-March 2, 2016, Los Angeles, CA https://resolver.caltech.edu/CaltechAUTHORS:20160606-074814901
Arnold, Anna R.; Grodick, Michael A. et al. (2016) DNA Charge Transport: from Chemical Principles to the Cell Cell Chemical Biology; Vol. 23; No. 1; https://resolver.caltech.edu/CaltechAUTHORS:20160307-094405041
Weidmann, Alyson G.; Barton, Jacqueline K. (2015) A Monofunctional Platinum Complex Coordinated to a Rhodium Metalloinsertor Selectively Binds Mismatched DNA in the Minor Groove Inorganic Chemistry; Vol. 54; No. 19; https://resolver.caltech.edu/CaltechAUTHORS:20150928-090441652
Furst, Ariel L.; Barton, Jacqueline K. (2015) DNA Electrochemistry Shows DNMT1 Methyltransferase Hyperactivity in Colorectal Tumors Chemistry and Biology; Vol. 22; No. 7; https://resolver.caltech.edu/CaltechAUTHORS:20150625-120207586
Furst, Ariel L.; Hill, Michael G. et al. (2015) A Multiplexed, Two-Electrode Platform for Biosensing Based on DNA-Mediated Charge Transport Langmuir; Vol. 31; No. 23; https://resolver.caltech.edu/CaltechAUTHORS:20150615-083148726
Weidmann, Alyson G.; Barton, Jacqueline K. (2015) Construction and application of a Rh-Pt DNA metalloinsertor conjugate Abstracts of Papers of the American Chemical Society; Vol. 249; In: 249th American Chemical Society National Meeting & Exposition, March 22-26, 2015, Denver, CO https://resolver.caltech.edu/CaltechAUTHORS:20150408-082055756
Grodick, Michael A.; Silva, Rebekah M. et al. (2015) DNA-mediated redox signaling by UvrC Abstracts of Papers of the American Chemical Society; Vol. 249; In: 249th American Chemical Society National Meeting & Exposition, March 22-26, 2015, Denver, CO https://resolver.caltech.edu/CaltechAUTHORS:20150424-080918487
Grodick, Michael A.; Zwang, Theodore J. et al. (2015) DNA-mediated signaling by the E. coli helicase, DinG Abstracts of Papers of the American Chemical Society; Vol. 249; In: 249th American Chemical Society National Meeting & Exposition, March 22-26, 2015, Denver, CO https://resolver.caltech.edu/CaltechAUTHORS:20150408-100209650
Komor, Alexis; Barton, Jacqueline K. (2015) Development of rhodium metalloinsertors as chemotherapeutic agents Abstracts of Papers of the American Chemical Society; Vol. 249; In: 249th American Chemical Society National Meeting & Exposition, March 22-26, 2015, Denver, CO https://resolver.caltech.edu/CaltechAUTHORS:20150414-131045800
Bartels, Phillip L.; Stodola, Joseph L. et al. (2015) Electron transfer and DNA replication: Assessing the functional role of the yeast DNA polymerase δ [4Fe- 4S] 2+ cluster Abstracts of Papers of the American Chemical Society; Vol. 249; In: 249th American Chemical Society National Meeting & Exposition, March 22-26, 2015, Denver, CO https://resolver.caltech.edu/CaltechAUTHORS:20150423-132051717
O'Brien, Elizabeth; Holt, Marilyn et al. (2015) Investigating the redox properties of human DNA primase Abstracts of Papers of the American Chemical Society; Vol. 249; In: 249th American Chemical Society National Meeting & Exposition, March 22-26, 2015, Denver, CO https://resolver.caltech.edu/CaltechAUTHORS:20150424-080637938
Furst, Ariel L.; Muren, Natalie et al. (2015) Label-free electrochemical detection of human methyltransferase from tumors Abstracts of Papers of the American Chemical Society; Vol. 249; In: 249th American Chemical Society National Meeting & Exposition, March 22-26, 2015, Denver, CO https://resolver.caltech.edu/CaltechAUTHORS:20150408-095933576
Boynton, Adam N.; McConnell, Anna J. et al. (2015) Luminescent ruthenium probe for DNA mismatches Abstracts of Papers of the American Chemical Society; Vol. 249; In: 249th American Chemical Society National Meeting & Exposition, March 22-26, 2015, Denver, CO https://resolver.caltech.edu/CaltechAUTHORS:20150414-131730851
Zwang, Theodore J.; Hurlimann, Sylvia et al. (2015) Magnetic field effects on charge transport through DNA Abstracts of Papers of the American Chemical Society; Vol. 249; In: 249th American Chemical Society National Meeting & Exposition, March 22-26, 2015, Denver, CO https://resolver.caltech.edu/CaltechAUTHORS:20150424-081137913
Boyle, Kelsey M.; Komor, Alexis et al. (2015) New family of rhodium metalloinsertors with improved selectivity and potency against DNA mismatch repair deficient cell lines Abstracts of Papers of the American Chemical Society; Vol. 249; In: 249th American Chemical Society National Meeting & Exposition, March 22-26, 2015, Denver, CO https://resolver.caltech.edu/CaltechAUTHORS:20150422-094854656
Schaefer, Kathryn N.; Geil, Wendy M. et al. (2015) Oxidation of p53 via DNA-mediated charge transport Abstracts of Papers of the American Chemical Society; Vol. 249; In: 249th American Chemical Society National Meeting & Exposition, March 22-26, 2015, Denver, CO https://resolver.caltech.edu/CaltechAUTHORS:20150423-131845489
Grodick, Michael A.; Muren, Natalie B. et al. (2015) DNA Charge Transport within the Cell Biochemistry; Vol. 54; No. 4; https://resolver.caltech.edu/CaltechAUTHORS:20150202-150621170
Schaefer, Kathryn N.; Geil, Wendy M. et al. (2015) Oxidation of p53 through DNA Charge Transport Involves a Network of Disulfides within the DNA-Binding Domain Biochemistry; Vol. 54; No. 3; https://resolver.caltech.edu/CaltechAUTHORS:20150120-083007297
Furst, Ariel L.; Hill, Michael G. et al. (2014) Electrocatalysis in DNA sensors Polyhedron; Vol. 84; https://resolver.caltech.edu/CaltechAUTHORS:20140811-081446490
Furst, Ariel L.; Muren, Natalie B. et al. (2014) Label-free electrochemical detection of human methyltransferase from tumors Proceedings of the National Academy of Sciences of the United States of America; Vol. 111; No. 42; https://resolver.caltech.edu/CaltechAUTHORS:20141009-075720084
Komor, Alexis C.; Barton, Jacqueline K. (2014) An Unusual Ligand Coordination Gives Rise to a New Family of Rhodium Metalloinsertors with Improved Selectivity and Potency Journal of the American Chemical Society; Vol. 136; No. 40; https://resolver.caltech.edu/CaltechAUTHORS:20140929-091130056
Weidmann, Alyson G.; Barton, Jacqueline K. (2014) Construction and Application of a Rh–Pt DNA Metalloinsertor Conjugate Inorganic Chemistry; Vol. 53; No. 15; https://resolver.caltech.edu/CaltechAUTHORS:20140721-085331031
Schaefer, Kathryn N.; Barton, Jacqueline K. (2014) DNA-Mediated Oxidation of p53 Biochemistry; Vol. 53; No. 21; https://resolver.caltech.edu/CaltechAUTHORS:20140528-093946157
Weidmann, Alyson G.; Komor, Alexis C. et al. (2014) Targeted Chemotherapy with Metal Complexes Comments on Inorganic Chemistry; Vol. 34; No. 3-4; https://resolver.caltech.edu/CaltechAUTHORS:20141024-100939620
Grodick, Michael A.; Segal, Helen M. et al. (2014) DNA-Mediated Signaling by Proteins with 4Fe−4S Clusters Is Necessary for Genomic Integrity Journal of the American Chemical Society; Vol. 136; No. 17; https://resolver.caltech.edu/CaltechAUTHORS:20140422-093606577
Barton, Jacqueline K. (2014) DNA signaling among proteins with iron-sulfur clusters Abstracts of Papers of the American Chemical Society; Vol. 247; In: 247th National Spring Meeting of the American-Chemical-Society (ACS), March 16-20, 2014, Dallas, TX https://resolver.caltech.edu/CaltechAUTHORS:20150316-095808555
Furst, Ariel L.; Hill, Michael G. et al. (2013) DNA-Modified Electrodes Fabricated Using Copper-Free Click Chemistry for Enhanced Protein Detection Langmuir; Vol. 29; No. 52; https://resolver.caltech.edu/CaltechAUTHORS:20131224-071741505
Furst, Ariel; Landefeld, Sally et al. (2013) Electrochemical Patterning and Detection of DNA Arrays on a Two-Electrode Platform Journal of the American Chemical Society; Vol. 135; No. 51; https://resolver.caltech.edu/CaltechAUTHORS:20131223-100408108
Muren, Natalie B.; Barton, Jacqueline K. (2013) Electrochemical Assay for the Signal-On Detection of Human DNA Methyltransferase Activity Journal of the American Chemical Society; Vol. 135; No. 44; https://resolver.caltech.edu/CaltechAUTHORS:20131205-093720227
Bailis, Julie M.; Gordon, Marcia L. et al. (2013) An Inducible, Isogenic Cancer Cell Line System for Targeting the State of Mismatch Repair Deficiency PLoS ONE; Vol. 8; No. 10; https://resolver.caltech.edu/CaltechAUTHORS:20131205-114027493
Arnold, Anna R.; Barton, Jacqueline K. (2013) DNA Protection by the Bacterial Ferritin Dps via DNA Charge Transport Journal of the American Chemical Society; Vol. 135; No. 42; https://resolver.caltech.edu/CaltechAUTHORS:20131206-091447174
Pheeney, Catrina G.; Barton, Jacqueline K. (2013) Intraduplex DNA-Mediated Electrochemistry of Covalently Tethered Redox-Active Reporters Journal of the American Chemical Society; Vol. 135; No. 40; https://resolver.caltech.edu/CaltechAUTHORS:20131105-140620927
McConnell, Anna J.; Song, Hang et al. (2013) Luminescence of [Ru(bpy)_2(dppz)]^(2+) Bound to RNA Mismatches Inorganic Chemistry; Vol. 52; No. 17; https://resolver.caltech.edu/CaltechAUTHORS:20131204-111813799
Pheeney, Catrina G.; Arnold, Anna R. et al. (2013) Multiplexed Electrochemistry of DNA-Bound Metalloproteins Journal of the American Chemical Society; Vol. 135; No. 32; https://resolver.caltech.edu/CaltechAUTHORS:20130913-110347612
Weidmann, Alyson G.; Komor, Alexis C. et al. (2013) Biological effects of simple changes in functionality on rhodium metalloinsertors Philosophical Transactions A: Mathematical, Physical and Engineering Sciences; Vol. 371; No. 1995; https://resolver.caltech.edu/CaltechAUTHORS:20130718-095506376
Komor, Alexis C.; Barton, Jacqueline K. (2013) The path for metal complexes to a DNA target Chemical Communications; Vol. 49; No. 35; https://resolver.caltech.edu/CaltechAUTHORS:20130503-130417175
Barton, Jacqueline K. (2013) DNA-Mediated Signaling Biophysical Journal; Vol. 104; No. 2; In: 57th Annual Meeting of the Biophysical-Society, February 2-6, 2013, Philadelphia, PA https://resolver.caltech.edu/CaltechAUTHORS:20130425-131548699
Komor, Alexis C.; Schneider, Curtis J. et al. (2012) Cell-Selective Biological Activity of Rhodium Metalloinsertors Correlates with Subcellular Localization Journal of the American Chemical Society; Vol. 134; No. 46; https://resolver.caltech.edu/CaltechAUTHORS:20130111-105340383
McConnell, Anna J.; Lim, Mi Hee et al. (2012) Luminescent Properties of Ruthenium(II) Complexes with Sterically Expansive Ligands Bound to DNA Defects Inorganic Chemistry; Vol. 51; No. 22; https://resolver.caltech.edu/CaltechAUTHORS:20130116-113416623
Muren, Natalie B.; Olmon, Eric D. et al. (2012) Solution, surface, and single molecule platforms for the study of DNA-mediated charge transport Physical Chemistry Chemical Physics; Vol. 14; No. 40; https://resolver.caltech.edu/CaltechAUTHORS:20120807-093450882
Sontz, Pamela A.; Muren, Natalie B. et al. (2012) DNA Charge Transport for Sensing and Signaling Accounts of Chemical Research; Vol. 45; No. 10; https://resolver.caltech.edu/CaltechAUTHORS:20121116-100524704
Song, Hang; Kaiser, Jens T. et al. (2012) Crystal structure of Δ-[Ru(bpy)_2dppz]^(2+) bound to mismatched DNA reveals side-by-side metalloinsertion and intercalation Nature Chemistry; Vol. 4; No. 8; https://resolver.caltech.edu/CaltechAUTHORS:20120824-131018535
Pheeney, Catrina G.; Guerra, Luis F. et al. (2012) DNA sensing by electrocatalysis with hemoglobin Proceedings of the National Academy of Sciences of the United States of America; Vol. 109; No. 29; https://resolver.caltech.edu/CaltechAUTHORS:20120810-143422701
Pheeney, Catrina G.; Barton, Jacqueline K. (2012) DNA Electrochemistry with Tethered Methylene Blue Langmuir; Vol. 28; No. 17; https://resolver.caltech.edu/CaltechAUTHORS:20120521-152748382
Sontz, Pamela A.; Mui, Timothy P. et al. (2012) DNA charge transport as a first step in coordinating the detection of lesions by repair proteins Proceedings of the National Academy of Sciences of the United States of America; Vol. 109; No. 6; https://resolver.caltech.edu/CaltechAUTHORS:20120228-100512207
Wang, Hanfei; Muren, Natalie B. et al. (2012) Transducing methyltransferase activity into electrical signals in a carbon nanotube–DNA device Chemical Science; Vol. 3; No. 1; https://resolver.caltech.edu/CaltechAUTHORS:20120104-142531511
Ernst, Russell J.; Komor, Alexis C. et al. (2011) Selective Cytotoxicity of Rhodium Metalloinsertors in Mismatch Repair-Deficient Cells Biochemistry; Vol. 50; No. 50; https://resolver.caltech.edu/CaltechAUTHORS:20120124-084500760
Olmon, Eric D.; Hill, Michael G. et al. (2011) Using Metal Complex Reduced States to Monitor the Oxidation of DNA Inorganic Chemistry; Vol. 50; No. 23; https://resolver.caltech.edu/CaltechAUTHORS:20120113-114638971
Mui, Timothy P.; Fuss, Jill O. et al. (2011) ATP-Stimulated, DNA-Mediated Redox Signaling by XPD, a DNA Repair and Transcription Helicase Journal of the American Chemical Society; Vol. 133; No. 41; https://resolver.caltech.edu/CaltechAUTHORS:20111116-102627735
Olmon, Eric D.; Sontz, Pamela A. et al. (2011) Charge Photoinjection in Intercalated and Covalently Bound [Re(CO)_(3)(dppz)(py)]^(+)–DNA Constructs Monitored by Time-Resolved Visible and Infrared Spectroscopy Journal of the American Chemical Society; Vol. 133; No. 34; https://resolver.caltech.edu/CaltechAUTHORS:20111115-142739242
Romano, Christine A.; Sontz, Pamela A. et al. (2011) Mutants of the Base Excision Repair Glycosylase, Endonuclease III: DNA Charge Transport as a First Step in Lesion Detection Biochemistry; Vol. 50; No. 27; https://resolver.caltech.edu/CaltechAUTHORS:20110725-095427413
Barton, Jacqueline K.; Olmon, Eric D. et al. (2011) Metal complexes for DNA-mediated charge transport Coordination Chemistry Reviews; Vol. 255; No. 7-8; https://resolver.caltech.edu/CaltechAUTHORS:20110506-101158648
Genereux, Joseph C.; Wuerth, Stephanie M. et al. (2011) Single-Step Charge Transport through DNA over Long Distances Journal of the American Chemical Society; Vol. 133; No. 11; https://resolver.caltech.edu/CaltechAUTHORS:20110502-100301067
Slinker, Jason D.; Muren, Natalie B. et al. (2011) DNA charge transport over 34 nm Nature Chemistry; Vol. 3; No. 3; https://resolver.caltech.edu/CaltechAUTHORS:20110322-141743600
Puckett, Cindy A.; Barton, Jacqueline K. (2010) Targeting a ruthenium complex to the nucleus with short peptides Bioorganic and Medicinal Chemistry Letters; Vol. 18; No. 10; https://resolver.caltech.edu/CaltechAUTHORS:20100602-153002681
Tanaka, Makiko; Elias, Benjamin et al. (2010) DNA-Mediated Electron Transfer in Naphthalene-Modified Oligonucleotides Journal of Organic Chemistry; Vol. 75; No. 8; https://resolver.caltech.edu/CaltechAUTHORS:20100517-152102648
Slinker, Jason D.; Muren, Natalie B. et al. (2010) Multiplexed DNA-Modified Electrodes Journal of the American Chemical Society; Vol. 132; No. 8; https://resolver.caltech.edu/CaltechAUTHORS:20100324-111156290
Genereux, Joseph C.; Barton, Jacqueline K. (2010) Mechanisms for DNA Charge Transport Chemical Reviews; Vol. 110; No. 3; https://resolver.caltech.edu/CaltechAUTHORS:20100407-134557359
Puckett, Cindy A.; Ernst, Russell J. et al. (2010) Exploring the cellular accumulation of metal complexes Dalton Transactions; Vol. 39; No. 5; https://resolver.caltech.edu/CaltechAUTHORS:20100216-153031939
Genereux, Joseph C.; Boal, Amie K. et al. (2010) DNA-Mediated Charge Transport in Redox Sensing and Signaling Journal of the American Chemical Society; Vol. 132; No. 3; https://resolver.caltech.edu/CaltechAUTHORS:20100405-093806861
Boal, Amie K.; Genereux, Joseph C. et al. (2009) Redox signaling between DNA repair proteins for efficient lesion detection Proceedings of the National Academy of Sciences of the United States of America; Vol. 106; No. 36; https://resolver.caltech.edu/CaltechAUTHORS:20090923-143133443
Lee, Paul E.; Demple, Bruce et al. (2009) DNA-mediated redox signaling for transcriptional activation of SoxR Proceedings of the National Academy of Sciences of the United States of America; Vol. 106; No. 32; https://resolver.caltech.edu/CaltechAUTHORS:20090828-231031224
Puckett, Cindy A.; Barton, Jacqueline K. (2009) Fluorescein Redirects a Ruthenium−Octaarginine Conjugate to the Nucleus Journal of the American Chemical Society; Vol. 131; No. 25; https://resolver.caltech.edu/CaltechAUTHORS:20090901-133357644
Lim, Mi Hee; Song, Hang et al. (2009) Sensitivity of Ru(bpy)_2dppz^(2+) Luminescence to DNA Defects Inorganic Chemistry; Vol. 48; No. 12; https://resolver.caltech.edu/CaltechAUTHORS:20090824-113601367
Zeglis, Brian M.; Pierre, Valérie C. et al. (2009) A Bulky Rhodium Complex Bound to an Adenosine-Adenosine DNA Mismatch: General Architecture of the Metalloinsertion Binding Mode Biochemistry; Vol. 48; No. 20; https://resolver.caltech.edu/CaltechAUTHORS:20090903-144603520
Genereux, Joseph C.; Barton, Jacqueline K. (2009) Molecular electronics: DNA charges ahead Nature Chemistry; Vol. 1; No. 2; https://resolver.caltech.edu/CaltechAUTHORS:20090828-231033057
Ernst, Russell J.; Song, Hang et al. (2009) DNA mismatch binding and antiproliferative activity of rhodium metalloinsertors Journal of the American Chemical Society; Vol. 131; No. 6; https://resolver.caltech.edu/CaltechAUTHORS:20090601-115902054
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Merino, Edward J.; Davis, Molly L. et al. (2009) Common Mitochondrial DNA Mutations Generated through DNA-Mediated Charge Transport Biochemistry; Vol. 48; No. 4; https://resolver.caltech.edu/CaltechAUTHORS:20090918-080256727
Gorodetsky, Alon A.; Buzzeo, Marisa C. et al. (2008) DNA-Mediated Electrochemistry Bioconjugate Chemistry; Vol. 19; No. 12; https://resolver.caltech.edu/CaltechAUTHORS:GORbc08
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Buzzeo, Marisa C.; Barton, Jacqueline K. (2008) Redmond Red as a Redox Probe for the DNA-Mediated Detection of Abasic Sites Bioconjugate Chemistry; Vol. 19; No. 11; https://resolver.caltech.edu/CaltechAUTHORS:BUZbc08
Genereux, Joseph C.; Augustyn, Katherine E. et al. (2008) Back-electron transfer suppresses the periodic length dependence of DNA-mediated charge transport across adenine tracts Journal of the American Chemical Society; Vol. 130; No. 45; https://resolver.caltech.edu/CaltechAUTHORS:20090504-093543546
Puckett, Cindy A.; Barton, Jacqueline K. (2008) Mechanism of cellular uptake of a ruthenium polypyridyl complex Biochemistry; Vol. 47; No. 45; https://resolver.caltech.edu/CaltechAUTHORS:PUCb08
Elias, Benjamin; Genereux, Joseph C. et al. (2008) Ping-Pong Electron Transfer through DNA Angewandte Chemie International Edition; Vol. 47; No. 47; https://resolver.caltech.edu/CaltechAUTHORS:ELIac08
Zeglis, Brian M.; Barton, Jacqueline K. (2008) Binding of Ru(bpy)_2(eilatin)^(2+)to Matched and Mismatched DNA Inorganic Chemistry; Vol. 47; No. 14; https://resolver.caltech.edu/CaltechAUTHORS:20160229-073032218
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Gorodetsky, Alon A.; Dietrich, Lars E. P. et al. (2008) DNA binding shifts the redox potential of the transcription factor SoxR Proceedings of the National Academy of Sciences of the United States of America; Vol. 105; No. 10; https://resolver.caltech.edu/CaltechAUTHORS:GORpnas08
Guo, Xuefeng; Gorodetsky, Alon A. et al. (2008) Conductivity of a single DNA duplex bridging a carbon nanotube gap Nature Nanotechnology; Vol. 3; No. 3; https://resolver.caltech.edu/CaltechAUTHORS:20160210-161130692
Merino, Edward J.; Barton, Jacqueline K. (2008) DNA Oxidation by Charge Transport in Mitochondria Biochemistry; Vol. 47; No. 6; https://resolver.caltech.edu/CaltechAUTHORS:20160229-120833212
Elias, Benjamin; Shao, Fangwei et al. (2008) Charge Migration along the DNA Duplex: Hole versus Electron Transport Journal of the American Chemical Society; Vol. 130; No. 4; https://resolver.caltech.edu/CaltechAUTHORS:20160226-135926234
Shao, Fangwei; Barton, Jacqueline K. (2007) Long-Range Electron and Hole Transport through DNA with Tethered Cyclometalated Iridium(III) Complexes Journal of the American Chemical Society; Vol. 129; No. 47; https://resolver.caltech.edu/CaltechAUTHORS:20160226-135927080
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Shao, Fangwei; Elias, Benjamin et al. (2007) Synthesis and Characterization of Iridium(III) Cyclometalated Complexes with Oligonucleotides: Insights into Redox Reactions with DNA Inorganic Chemistry; Vol. 46; No. 24; https://resolver.caltech.edu/CaltechAUTHORS:20160229-073228331
Lim, Mi Hee; Lau, Irvin H. et al. (2007) DNA Strand Cleavage near a CC Mismatch Directed by a Metalloinsertor Inorganic Chemistry; Vol. 46; No. 23; https://resolver.caltech.edu/CaltechAUTHORS:20160302-071129473
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Gorodetsky, Alon A.; Green, Omar et al. (2007) Coupling into the Base Pair Stack Is Necessary for DNA-Mediated Electrochemistry Bioconjugate Chemistry; Vol. 18; No. 5; https://resolver.caltech.edu/CaltechAUTHORS:20160229-103205895
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Gorodetsky, Alon A.; Barton, Jacqueline K. (2007) DNA-Mediated Electrochemistry of Disulfides on Graphite Journal of the American Chemical Society; Vol. 129; No. 19; https://resolver.caltech.edu/CaltechAUTHORS:20160229-085218437
Merino, Edward J.; Barton, Jacqueline K. (2007) Oxidation by DNA Charge Transport Damages Conserved Sequence Block II, a Regulatory Element in Mitochondrial DNA Biochemistry; Vol. 46; No. 10; https://resolver.caltech.edu/CaltechAUTHORS:20160217-105103863
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Ceres, Donato M.; Udit, Andrew K. et al. (2007) Differential Ionic Permeation of DNA-Modified Electrodes Journal of Physical Chemistry B; Vol. 111; No. 3; https://resolver.caltech.edu/CaltechAUTHORS:20160226-135928097
Puckett, Cindy A.; Barton, Jacqueline K. (2007) Methods to Explore Cellular Uptake of Ruthenium Complexes Journal of the American Chemical Society; Vol. 129; No. 1; https://resolver.caltech.edu/CaltechAUTHORS:20160229-085221379
Pierre, Valerie C.; Kaiser, Jens T. et al. (2007) Insights into finding a mismatch through the structure of a mispaired DNA bound by a rhodium intercalator Proceedings of the National Academy of Sciences of the United States of America; Vol. 104; No. 2; https://resolver.caltech.edu/CaltechAUTHORS:PIEpnas07
Hart, Jonathan R.; Glebov, Oleg et al. (2006) DNA mismatch-specific targeting and hypersensitivity of mismatch-repair-deficient cells to bulky rhodium(III) intercalators Proceedings of the National Academy of Sciences of the United States of America; Vol. 103; No. 42; https://resolver.caltech.edu/CaltechAUTHORS:HARpnas06
Brunner, Jens; Barton, Jacqueline K. (2006) Targeting DNA Mismatches with Rhodium Intercalators Functionalized with a Cell-Penetrating Peptide Biochemistry; Vol. 45; No. 40; https://resolver.caltech.edu/CaltechAUTHORS:20160229-103206591
Gorodetsky, Alon A.; Boal, Amie K. et al. (2006) Direct Electrochemistry of Endonuclease III in the Presence and Absence of DNA Journal of the American Chemical Society; Vol. 128; No. 37; https://resolver.caltech.edu/CaltechAUTHORS:20160209-124711381
Gorodetsky, Alon A.; Barton, Jacqueline K. (2006) Electrochemistry Using Self-Assembled DNA Monolayers on Highly Oriented Pyrolytic Graphite Langmuir; Vol. 22; No. 18; https://resolver.caltech.edu/CaltechAUTHORS:20160229-085222529
Brunner, Jens; Barton, Jacqueline K. (2006) Site-Specific DNA Photocleavage by Rhodium Intercalators Analyzed by MALDI-TOF Mass Spectrometry Journal of the American Chemical Society; Vol. 128; No. 21; https://resolver.caltech.edu/CaltechAUTHORS:20160229-085221075
Zeglis, Brian M.; Barton, Jacqueline K. (2006) A Mismatch-Selective Bifunctional Rhodium−Oregon Green Conjugate: A Fluorescent Probe for Mismatched DNA Journal of the American Chemical Society; Vol. 128; No. 17; https://resolver.caltech.edu/CaltechAUTHORS:20160209-124007376
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Takada, Tadao; Barton, Jacqueline K. (2005) DNA Charge Transport Leading to Disulfide Bond Formation Journal of the American Chemical Society; Vol. 127; No. 35; https://resolver.caltech.edu/CaltechAUTHORS:20160209-123604635
DeRosa, Maria C.; Sancar, Aziz et al. (2005) Electrically monitoring DNA repair by photolyase Proceedings of the National Academy of Sciences of the United States of America; Vol. 102; No. 31; https://resolver.caltech.edu/CaltechAUTHORS:DERpnas05
Liu, Tao; Barton, Jacqueline K. (2005) DNA Electrochemistry through the Base Pairs Not the Sugar−Phosphate Backbone Journal of the American Chemical Society; Vol. 127; No. 29; https://resolver.caltech.edu/CaltechAUTHORS:20160209-123230374
Boal, Amie K.; Yavin, Eylon et al. (2005) DNA-Bound Redox Activity of DNA Repair Glycosylases Containing [4Fe-4S] Clusters Biochemistry; Vol. 44; No. 23; https://resolver.caltech.edu/CaltechAUTHORS:20160229-103206847
Yavin, Eylon; Boal, Amie K. et al. (2005) Protein-DNA charge transport: Redox activation of a DNA repair protein by guanine radical Proceedings of the National Academy of Sciences of the United States of America; Vol. 102; No. 10; https://resolver.caltech.edu/CaltechAUTHORS:YAVpnas05
Boal, Amie K.; Barton, Jacqueline K. (2005) Electrochemical Detection of Lesions in DNA Bioconjugate Chemistry; Vol. 16; No. 2; https://resolver.caltech.edu/CaltechAUTHORS:20160226-120946590
Shao, Fangwei; O'Neill, Melanie A. et al. (2004) Long-range oxidative damage to cytosines in duplex DNA Proceedings of the National Academy of Sciences of the United States of America; Vol. 101; No. 52; https://resolver.caltech.edu/CaltechAUTHORS:SHApnas04
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Petitjean, Anne; Barton, Jacqueline K. (2004) Tuning the DNA Reactivity of cis-Platinum: Conjugation to a Mismatch-Specific Metallointercalator Journal of the American Chemical Society; Vol. 126; No. 45; https://resolver.caltech.edu/CaltechAUTHORS:20160209-121156848
O'Neill, Melanie A.; Barton, Jacqueline K. (2004) DNA-Mediated Charge Transport Requires Conformational Motion of the DNA Bases: Elimination of Charge Transport in Rigid Glasses at 77 K Journal of the American Chemical Society; Vol. 126; No. 41; https://resolver.caltech.edu/CaltechAUTHORS:20170421-084130900
Hart, Jonathan R.; Johnson, Martin D. et al. (2004) Single-nucleotide polymorphism discovery by targeted DNA photocleavage Proceedings of the National Academy of Sciences of the United States of America; Vol. 101; No. 39; https://resolver.caltech.edu/CaltechAUTHORS:HARpnas04
O'Neill, Melanie A.; Barton, Jacqueline K. (2004) DNA Charge Transport: Conformationally Gated Hopping through Stacked Domains Journal of the American Chemical Society; Vol. 126; No. 37; https://resolver.caltech.edu/CaltechAUTHORS:20160209-122044703
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Delaney, Sarah; Yoo, Jae et al. (2004) Charge equilibration between two distinct sites in double helical DNA Proceedings of the National Academy of Sciences of the United States of America; Vol. 101; No. 29; https://resolver.caltech.edu/CaltechAUTHORS:DELpnas04
Schatzschneider, Ulrich; Barton, Jacqueline K. (2004) Bifunctional Rhodium Intercalator Conjugates as Mismatch-Directing DNA Alkylating Agents Journal of the American Chemical Society; Vol. 126; No. 28; https://resolver.caltech.edu/CaltechAUTHORS:20160209-121614706
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O'Neill, Melanie A.; Dohno, Chikara et al. (2004) Direct Chemical Evidence for Charge Transfer between Photoexcited 2-Aminopurine and Guanine in Duplex DNA Journal of the American Chemical Society; Vol. 126; No. 5; https://resolver.caltech.edu/CaltechAUTHORS:20160208-163052817
Bhattacharya, Pratip K.; Lawson, Holly J. et al. (2003) ^1H NMR Studies of Nickel(II) Complexes Bound to Oligonucleotides: A Novel Technique for Distinguishing the Binding Locations of Metal Complexes in DNA Inorganic Chemistry; Vol. 42; No. 26; https://resolver.caltech.edu/CaltechAUTHORS:20160229-120833527
Ceres, Donato M.; Barton, Jacqueline K. (2003) In Situ Scanning Tunneling Microscopy of DNA-Modified Gold Surfaces: Bias and Mismatch Dependence Journal of the American Chemical Society; Vol. 125; No. 49; https://resolver.caltech.edu/CaltechAUTHORS:20160229-085221665
Delaney, Sarah; Barton, Jacqueline K. (2003) Charge Transport in DNA Duplex/Quadruplex Conjugates Biochemistry; Vol. 42; No. 48; https://resolver.caltech.edu/CaltechAUTHORS:20160229-112429045
O'Neill, Melanie A.; Becker, Hans-Christian et al. (2003) Ultrafast Dynamics in DNA-Mediated Electron Transfer: Base Gating and the Role of Temperature Angewandte Chemie International Edition; Vol. 42; No. 47; https://resolver.caltech.edu/CaltechAUTHORS:20160212-080416474
Boon, Elizabeth M.; Livingston, Alison L. et al. (2003) DNA-mediated charge transport for DNA repair Proceedings of the National Academy of Sciences of the United States of America; Vol. 100; No. 22; https://resolver.caltech.edu/CaltechAUTHORS:BOOpnas03
Boon, Elizabeth M.; Barton, Jacqueline K. et al. (2003) Reduction of Ferricyanide by Methylene Blue at a DNA-Modified Rotating-Disk Electrode Langmuir; Vol. 19; No. 22; https://resolver.caltech.edu/CaltechAUTHORS:20170427-100416986
Boon, Elizabeth M.; Barton, Jacqueline K. (2003) DNA Electrochemistry as a Probe of Base Pair Stacking in A-, B-, and Z-Form DNA Bioconjugate Chemistry; Vol. 14; No. 6; https://resolver.caltech.edu/CaltechAUTHORS:20160219-115028115
Boon, Elizabeth M.; Jackson, Nicole M. et al. (2003) Intercalative Stacking: A Critical Feature of DNA Charge-Transport Electrochemistry Journal of Physical Chemistry B; Vol. 107; No. 42; https://resolver.caltech.edu/CaltechAUTHORS:20170523-145321462
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Delaney, Sarah; Barton, Jacqueline K. (2003) Long-Range DNA Charge Transport Journal of Organic Chemistry; Vol. 68; No. 17; https://resolver.caltech.edu/CaltechAUTHORS:20160226-135927857
Dohno, Chikara; Stemp, Eric D. A. et al. (2003) Fast Back Electron Transfer Prevents Guanine Damage by Photoexcited Thionine Bound to DNA Journal of the American Chemical Society; Vol. 125; No. 32; https://resolver.caltech.edu/CaltechAUTHORS:20160208-162638030
Yoo, Jae; Delaney, Sarah et al. (2003) Rapid Radical Formation by DNA Charge Transport through Sequences Lacking Intervening Guanines Journal of the American Chemical Society; Vol. 125; No. 22; https://resolver.caltech.edu/CaltechAUTHORS:20160208-152837570
Junicke, Henrik; Hart, Jonathan R. et al. (2003) A rhodium(III) complex for high-affinity DNA base-pair mismatch recognition Proceedings of the National Academy of Sciences of the United States of America; Vol. 100; No. 7; https://resolver.caltech.edu/CaltechAUTHORS:JUNpnas03
O'Neill, Melanie A.; Barton, Jacqueline K. (2002) Effects of strand and directional asymmetry on base-base coupling and charge transfer in double-helical DNA Proceedings of the National Academy of Sciences of the United States of America; Vol. 99; No. 26; https://resolver.caltech.edu/CaltechAUTHORS:ONEpnas02
O'Neill, Melanie A.; Barton, Jacqueline K. (2002) 2-Aminopurine: A Probe of Structural Dynamics and Charge Transfer in DNA and DNA:RNA Hybrids Journal of the American Chemical Society; Vol. 124; No. 44; https://resolver.caltech.edu/CaltechAUTHORS:20160229-085221976
Bhattacharya, Pratip K.; Cha, Julie et al. (2002) 1H NMR determination of base-pair lifetimes in oligonucleotides containing single base mismatches Nucleic Acids Research; Vol. 30; No. 21; https://resolver.caltech.edu/CaltechAUTHORS:BHAnar02
Copeland, Kimberly D.; Lueras, Alexis M. K. et al. (2002) DNA Cross-Linking with Metallointercalator−Peptide Conjugates Biochemistry; Vol. 41; No. 42; https://resolver.caltech.edu/CaltechAUTHORS:20160210-155329163
Boon, Elizabeth M.; Barton, Jacqueline K. et al. (2002) An Electrochemical Probe of DNA Stacking in an Antisense Oligonucleotide Containing a C3'-endo-Locked Sugar Angewandte Chemie International Edition; Vol. 41; No. 18; https://resolver.caltech.edu/CaltechAUTHORS:20160210-154230344
Pascaly, Matthias; Yoo, Jae et al. (2002) DNA Mediated Charge Transport: Characterization of a DNA Radical Localized at an Artificial Nucleic Acid Base Journal of the American Chemical Society; Vol. 124; No. 31; https://resolver.caltech.edu/CaltechAUTHORS:20160210-155947915
Boon, Elizabeth M.; Pope, Mary Ann et al. (2002) DNA-Mediated Charge Transport as a Probe of MutY/DNA Interaction Biochemistry; Vol. 41; No. 26; https://resolver.caltech.edu/CaltechAUTHORS:20160210-160315353
Boon, Elizabeth M.; Barton, Jacqueline K. (2002) Charge transport in DNA Current Opinion in Structural Biology; Vol. 12; No. 3; https://resolver.caltech.edu/CaltechAUTHORS:20160127-111126226
Delaney, Sarah; Pascaly, Matthias et al. (2002) Oxidative Damage by Ruthenium Complexes Containing the Dipyridophenazine Ligand or Its Derivatives: A Focus on Intercalation Inorganic Chemistry; Vol. 41; No. 7; https://resolver.caltech.edu/CaltechAUTHORS:20160209-164250806
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Williams, Tashica T.; Barton, Jacqueline K. (2002) The Effect of Varied Ion Distributions on Long-Range DNA Charge Transport Journal of the American Chemical Society; Vol. 124; No. 9; https://resolver.caltech.edu/CaltechAUTHORS:20160208-152444728
Boon, Elizabeth M.; Salas, Julia E. et al. (2002) An electrical probe of protein-DNA interactions on DNA-modified surfaces Nature Biotechnology; Vol. 20; No. 3; https://resolver.caltech.edu/CaltechAUTHORS:20150401-111610690
Copeland, Kimberly D.; Fitzsimons, Marilena P. et al. (2002) DNA Hydrolysis and Oxidative Cleavage by Metal-Binding Peptides Tethered to Rhodium Intercalators Biochemistry; Vol. 41; No. 1; https://resolver.caltech.edu/CaltechAUTHORS:20160209-161227098
Boon, Elizabeth M.; Kisko, Jennifer L. et al. (2002) Detection of DNA Base Mismatches Using DNA Intercalators In: Redox Cell Biology and Genetics Part B; Methods in Enzymology; Vol. 353; https://resolver.caltech.edu/CaltechAUTHORS:20160127-120857206
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Stinner, Christine; Wightman, Matthew D. et al. (2001) Synthesis and Spectroelectrochemistry of Ir(bpy)(phen)(phi)^(3+), a Tris(heteroleptic) Metallointercalator Inorganic Chemistry; Vol. 40; No. 20; https://resolver.caltech.edu/CaltechAUTHORS:20160129-155405893
Sam, Mui; Boon, Elizabeth M. et al. (2001) Morphology of 15-mer Duplexes Tethered to Au(111) Probed Using Scanning Probe Microscopy Langmuir; Vol. 17; No. 19; https://resolver.caltech.edu/CaltechAUTHORS:20170427-102105912
Bhattacharya, Pratip K.; Barton, Jacqueline K. (2001) Influence of Intervening Mismatches on Long-Range Guanine Oxidation in DNA Duplexes Journal of the American Chemical Society; Vol. 123; No. 36; https://resolver.caltech.edu/CaltechAUTHORS:20160208-152036536
Odom, Duncan T.; Barton, Jacqueline K. (2001) Long-Range Oxidative Damage in DNA/RNA Duplexes Biochemistry; Vol. 40; No. 30; https://resolver.caltech.edu/CaltechAUTHORS:20160209-160654855
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Rajski, Scott R.; Barton, Jacqueline K. (2001) How Different DNA-Binding Proteins Affect Long-Range Oxidative Damage to DNA Biochemistry; Vol. 40; No. 18; https://resolver.caltech.edu/CaltechAUTHORS:20160209-152857175
Wan, Chaozhi; Fiebig, Torsten et al. (2000) Femtosecond direct observation of charge transfer between bases in DNA Proceedings of the National Academy of Sciences of the United States of America; Vol. 97; No. 26; https://resolver.caltech.edu/CaltechAUTHORS:WANpnas00
Kelley, Shana O.; Orellana, Guillermo et al. (2000) Luminescence quenching by DNA-bound viologens: effect of reactant identity on efficiency and dynamics of electron transfer in DNA Journal of Photochemistry and Photobiology B: Biology; Vol. 58; No. 2-3; https://resolver.caltech.edu/CaltechAUTHORS:20160125-195239389
Kisko, Jennifer L.; Barton, Jacqueline K. (2000) Recognition of DNA Base Pair Mismatches by a Cyclometalated Rh(III) Intercalator Inorganic Chemistry; Vol. 39; No. 21; https://resolver.caltech.edu/CaltechAUTHORS:20160209-152113459
Boon, Elizabeth M.; Ceres, Donato M. et al. (2000) Mutation detection by electrocatalysis at DNA-modified electrodes Nature Biotechnology; Vol. 18; No. 12; https://resolver.caltech.edu/CaltechAUTHORS:20150408-152315146
Williams, Tashica T.; Odom, Duncan T. et al. (2000) Variations in DNA Charge Transport with Nucleotide Composition and Sequence Journal of the American Chemical Society; Vol. 122; No. 37; https://resolver.caltech.edu/CaltechAUTHORS:20170404-082323148
Vicic, David A.; Odom, Duncan T. et al. (2000) Oxidative Repair of a Thymine Dimer in DNA from a Distance by a Covalently Linked Organic Intercalator Journal of the American Chemical Society; Vol. 122; No. 36; https://resolver.caltech.edu/CaltechAUTHORS:20170404-094144114
Schiemann, Olav; Turro, Nicholas J. et al. (2000) EPR Detection of Guanine Radicals in a DNA Duplex under Biological Conditions: Selective Base Oxidation by Ru(phen)_2dppz^(3+)Using the Flash-Quench Technique Journal of Physical Chemistry B; Vol. 104; No. 30; https://resolver.caltech.edu/CaltechAUTHORS:20170517-070820804
Stemp, Eric D. A.; Barton, Jacqueline K. (2000) The Flash−Quench Technique in Protein−DNA Electron Transfer: Reduction of the Guanine Radical by Ferrocytochrome c Inorganic Chemistry; Vol. 39; No. 17; https://resolver.caltech.edu/CaltechAUTHORS:20160209-151255707
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Wagenknecht, Hans-Achim; Stemp, Eric D. A. et al. (2000) DNA-Bound Peptide Radicals Generated through DNA-Mediated Electron Transport Biochemistry; Vol. 39; No. 18; https://resolver.caltech.edu/CaltechAUTHORS:20160209-145158250
Núñez, Megan E.; Noyes, Katherine T. et al. (2000) Long-Range Guanine Oxidation in DNA Restriction Fragments by a Triplex-Directed Naphthalene Diimide Intercalator Biochemistry; Vol. 39; No. 20; https://resolver.caltech.edu/CaltechAUTHORS:20160209-142945831
Jackson, Brian A.; Barton, Jacqueline K. (2000) Recognition of Base Mismatches in DNA by 5,6-Chrysenequinone Diimine Complexes of Rhodium(III): A Proposed Mechanism for Preferential Binding in Destabilized Regions of the Double Helix Biochemistry; Vol. 39; No. 20; https://resolver.caltech.edu/CaltechAUTHORS:20160209-144358626
Núñez, Megan E.; Barton, Jacqueline K. (2000) Probing DNA charge transport with metallointercalators Current Opinion in Chemical Biology; Vol. 4; No. 2; https://resolver.caltech.edu/CaltechAUTHORS:20160129-080803438
Kielkopf, Clara L.; Erkkila, Kathryn E. et al. (2000) Structure of a photoactive rhodium complex intercalated into DNA Nature Structural Biology; Vol. 7; No. 2; https://resolver.caltech.edu/CaltechAUTHORS:20150108-155222366
Rajski, Scott R.; Jackson, Brian A. et al. (2000) DNA repair: models for damage and mismatch recognition Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis; Vol. 447; No. 1; https://resolver.caltech.edu/CaltechAUTHORS:20160127-111126763
Wagenknecht, Hans-Achim; Stemp, Eric D. A. et al. (2000) Evidence of Electron Transfer from Peptides to DNA: Oxidation of DNA-Bound Tryptophan Using the Flash-Quench Technique Journal of the American Chemical Society; Vol. 122; No. 1; https://resolver.caltech.edu/CaltechAUTHORS:20170425-131010289
Stemp, Eric D. A.; Holmlin, R. Erik et al. (2000) Electron transfer between metal complexes bound to DNA: variations in sequence, donor, and metal binding mode Inorganica Chimica Acta; Vol. 297; No. 1-2; https://resolver.caltech.edu/CaltechAUTHORS:20160323-092524330
Rajski, Scott R.; Barton, Jacqueline K. (2000) DNA-Mediated Electron Transfer: A Sensitive Probe of DNA-Protein Interactions Journal of Biomolecular Structure and Dynamics; Vol. 17; No. S1; https://resolver.caltech.edu/CaltechAUTHORS:20160125-195950967
Núñez, Megan E.; Rajski, Scott R. et al. (2000) Damage to DNA by long-range charge transport In: Singlet Oxygen, UV-A, and Ozone; Methods in Enzymology; Vol. 319; https://resolver.caltech.edu/CaltechAUTHORS:20160127-111127012
Jackson, Brian A.; Henling, Lawrence M. et al. (1999) Spectral and Structural Characterization of 5,6-Chrysenequinone Diimine Complexes of Rhodium(III): Evidence for a pH-Dependent Ligand Conformational Switch Inorganic Chemistry; Vol. 38; No. 26; https://resolver.caltech.edu/CaltechAUTHORS:20160412-081002999
Kelley, Shana O.; Boon, Elizabeth M. et al. (1999) Single-base mismatch detection based on charge transduction through DNA Nucleic Acids Research; Vol. 27; No. 24; https://resolver.caltech.edu/CaltechAUTHORS:KELnar99
Holmlin, R. Erik; Dandliker, Peter J. et al. (1999) Synthesis of Metallointercalator−DNA Conjugates on a Solid Support Bioconjugate Chemistry; Vol. 10; No. 6; https://resolver.caltech.edu/CaltechAUTHORS:20180202-151812038
Holmlin, R. Erik; Dandliker, Peter J. et al. (1999) Synthesis of Metallointercalator−DNA Conjugates on a Solid Support Bioconjugate Chemistry; Vol. 10; No. 6; https://resolver.caltech.edu/CaltechAUTHORS:20160405-150256286
Erkkila, Kathryn E.; Odom, Duncan T. et al. (1999) Recognition and Reaction of Metallointercalators with DNA Chemical Reviews; Vol. 99; No. 9; https://resolver.caltech.edu/CaltechAUTHORS:20160407-115524676
Hastings, Curtis A.; Barton, Jacqueline K. (1999) Perturbing the DNA Sequence Selectivity of Metallointercalator−Peptide Conjugates by Single Amino Acid Modification Biochemistry; Vol. 38; No. 31; https://resolver.caltech.edu/CaltechAUTHORS:20160407-115523468
Wan, Chaozhi; Fiebig, Torsten et al. (1999) Femtosecond dynamics of DNA-mediated electron transfer Proceedings of the National Academy of Sciences of the United States of America; Vol. 96; No. 11; https://resolver.caltech.edu/CaltechAUTHORS:WANpnas99
Odom, Duncan T.; Parker, Carl S. et al. (1999) Site-Specific Inhibition of Transcription Factor Binding to DNA by a Metallointercalator Biochemistry; Vol. 38; No. 16; https://resolver.caltech.edu/CaltechAUTHORS:20160407-115524241
Jackson, Brian A.; Alekseyev, Viktor Y. et al. (1999) A Versatile Mismatch Recognition Agent: Specific Cleavage of a Plasmid DNA at a Single Base Mispair Biochemistry; Vol. 38; No. 15; https://resolver.caltech.edu/CaltechAUTHORS:20160407-115523781
Kelley, Shana O.; Jackson, Nicole M. et al. (1999) Long-Range Electron Transfer through DNA Films Angewandte Chemie International Edition; Vol. 38; No. 7; https://resolver.caltech.edu/CaltechAUTHORS:20180507-111150983
Houser, Robert P.; Fitzsimons, Marilena P. et al. (1999) Metal-Dependent Intramolecular Chiral Induction: The Zn^(2+) Complex of an Ethidium−Peptide Conjugate Inorganic Chemistry; Vol. 38; No. 6; https://resolver.caltech.edu/CaltechAUTHORS:20160407-115522678
Fiebig, Torsten; Wan, Chaozhi et al. (1999) Femtosecond dynamics of the DNA intercalator ethidium and electron transfer with mononucleotides in water Proceedings of the National Academy of Sciences of the United States of America; Vol. 96; No. 4; https://resolver.caltech.edu/CaltechAUTHORS:FIEpnas99
Núñez, Megan E.; Hall, Daniel B. et al. (1999) Long-range oxidative damage to DNA: Effects of distance and sequence Chemistry and Biology; Vol. 6; No. 2; https://resolver.caltech.edu/CaltechAUTHORS:20160330-112528546
Kelley, Shana O.; Barton, Jacqueline K. (1999) Electron Transfer Between Bases in Double Helical DNA Science; Vol. 283; No. 5400; https://resolver.caltech.edu/CaltechAUTHORS:20141124-090349421
Holmlin, R. Erik; Yao, Johanna A. et al. (1999) Dipyridophenazine Complexes of Os(II) as Red-Emitting DNA Probes: Synthesis, Characterization, and Photophysical Properties Inorganic Chemistry; Vol. 38; No. 1; https://resolver.caltech.edu/CaltechAUTHORS:20180524-162758977
Terbrueggen, Robert H.; Johann, Timothy W. et al. (1998) Functionalized Rhodium Intercalators for DNA Recognition Inorganic Chemistry; Vol. 37; No. 26; https://resolver.caltech.edu/CaltechAUTHORS:20160407-115522359
Kelley, Shana O.; Barton, Jacqueline K. et al. (1998) Orienting DNA Helices on Gold Using Applied Electric Fields Langmuir; Vol. 14; No. 24; https://resolver.caltech.edu/CaltechAUTHORS:20180719-155943234
Franklin, Sonya J.; Barton, Jacqueline K. (1998) Differential DNA Recognition by the Enantiomers of 1-Rh(MGP)_2phi: A Combination of Shape Selection and Direct Readout Biochemistry; Vol. 37; No. 46; https://resolver.caltech.edu/CaltechAUTHORS:20160407-115523216
Hall, Daniel B.; Kelley, Shana O. et al. (1998) Long-Range and Short-Range Oxidative Damage to DNA: Photoinduced Damage to Guanines in Ethidium−DNA Assemblies Biochemistry; Vol. 37; No. 45; https://resolver.caltech.edu/CaltechAUTHORS:20160407-115522973
Franklin, Sonya J.; Treadway, Christopher R. et al. (1998) A Reinvestigation by Circular Dichroism and NMR: Ruthenium(II) and Rhodium(III) Metallointercalators Do Not Bind Cooperatively to DNA Inorganic Chemistry; Vol. 37; No. 20; https://resolver.caltech.edu/CaltechAUTHORS:20180524-163555321
Chen, Wei; Turro, Claudia et al. (1998) Reply to the Comment on "Resonance Raman Investigation of Ru(phen)_2dppz^(2+) and Related Complexes in Water and in the Presence of DNA" Journal of Physical Chemistry B; Vol. 102; No. 32; https://resolver.caltech.edu/CaltechAUTHORS:20180719-163630672
Kelley, Shana O.; Barton, Jacqueline K. (1998) DNA-mediated electron transfer from a modified base to ethidium: π-stacking as a modulator of reactivity Chemistry and Biology; Vol. 5; No. 8; https://resolver.caltech.edu/CaltechAUTHORS:20160330-112529738
Mürner, Hansruedi; Jackson, Brian A. et al. (1998) A Versatile Synthetic Approach to Rhodium(III) Diimine Metallointercalators: Condensation of o-Quinones with Coordinated cis-Ammines Inorganic Chemistry; Vol. 37; No. 12; https://resolver.caltech.edu/CaltechAUTHORS:20180524-164125514
Lim, Ai Ching; Barton, Jacqueline K. (1998) Rh(Phen)_2Phi^(3+) as a Shape-Selective Probe of Triple Helices Biochemistry; Vol. 37; No. 25; https://resolver.caltech.edu/CaltechAUTHORS:20160407-101623917
Dandliker, Peter J.; Núñez, Megan E. et al. (1998) Oxidative Charge Transfer To Repair Thymine Dimers and Damage Guanine Bases in DNA Assemblies Containing Tethered Metallointercalators Biochemistry; Vol. 37; No. 18; https://resolver.caltech.edu/CaltechAUTHORS:20160407-101621786
Barton, Jacqueline K. (1998) DNA-mediated electron transfer: Chemistry at a distance Pure and Applied Chemistry; Vol. 70; No. 4; In: International Conference on Bioinorganic Chemistry, International Conference on Bioinorganic Chemistry (ICBC), July 27-August 1, 1997, Yokohama, Japan https://resolver.caltech.edu/CaltechAUTHORS:20180808-100416627
Holmlin, R. Erik; Stemp, Eric D. A. et al. (1998) Ru(phen)_2dppz^(2+) Luminescence: Dependence on DNA Sequences and Groove-Binding Agents Inorganic Chemistry; Vol. 37; No. 1; https://resolver.caltech.edu/CaltechAUTHORS:20160411-102728744
Lim, Ai Ching; Barton, Jacqueline K. (1997) Targeting the Tat-Binding Site of Bovine Immunodeficiency Virus TAR RNA with a Shape-Selective Rhodium Complex Bioorganic and Medicinal Chemistry; Vol. 5; No. 6; https://resolver.caltech.edu/CaltechAUTHORS:20160324-071825486
Arkin, Michelle R.; Stemp, Eric D. A. et al. (1997) Long-range oxidation of guanine by Ru(III) in duplex DNA Chemistry and Biology; Vol. 4; No. 5; https://resolver.caltech.edu/CaltechAUTHORS:20160330-112529436
Dandliker, Peter J.; Holmlin, R. Erik et al. (1997) Oxidative Thymine Dimer Repair in the DNA Helix Science; Vol. 275; No. 5305; https://resolver.caltech.edu/CaltechAUTHORS:20141126-103406641
Kelley, Shana O.; Barton, Jacqueline K. et al. (1997) Electrochemistry of Methylene Blue Bound to a DNA-Modified Electrode Bioconjugate Chemistry; Vol. 8; No. 1; https://resolver.caltech.edu/CaltechAUTHORS:20160405-110030531
Dupureur, Cynthia M.; Barton, Jacqueline K. (1997) Structural Studies of Λ- and Δ-[Ru(phen)_2dppz]^(2+)Bound to d(GTCGAC)_2: Characterization of Enantioselective Intercalation Inorganic Chemistry; Vol. 36; No. 1; https://resolver.caltech.edu/CaltechAUTHORS:20180515-132544141
Hall, Daniel B.; Holmlin, R. Erik et al. (1996) Oxidative DNA damage through long-range electron transfer Nature; Vol. 382; No. 6593; https://resolver.caltech.edu/CaltechAUTHORS:20150617-092516497
Arkin, M. R.; Stemp, E. D. A. et al. (1996) Rates of DNA-Mediated Electron Transfer Between Metallointercalators Science; Vol. 273; No. 5274; https://resolver.caltech.edu/CaltechAUTHORS:20141211-093844438
Holmlin, R. Erik; Stemp, Eric D. A. et al. (1996) Os(phen)_2dppz^(2+) in Photoinduced DNA-Mediated Electron Transfer Reactions Journal of the American Chemical Society; Vol. 118; No. 22; https://resolver.caltech.edu/CaltechAUTHORS:20171107-133435500
Turro, Claudia; Evenzahav, Ariella et al. (1996) Excited state properties of Rh(phi)_2(phen)^(3+) and related complexes: a strong photooxidant Inorganica Chimica Acta; Vol. 243; No. 1; https://resolver.caltech.edu/CaltechAUTHORS:20170408-162652102
Johann, Timothy W.; Barton, Jacqueline K. (1996) Recognition of DNA by Octahedral Coordination Complexes Philosophical Transactions A: Mathematical, Physical and Engineering Sciences; Vol. 354; No. 1706; https://resolver.caltech.edu/CaltechAUTHORS:20150107-105109518
Shields, Thomas P.; Barton, Jacqueline K. (1995) Sequence-Selective DNA Recognition and Photocleavage: A Comparison of Enantiomers of Rh(en)_2phi^(3+) Biochemistry; Vol. 34; No. 46; https://resolver.caltech.edu/CaltechAUTHORS:20160405-140026070
Shields, Thomas P.; Barton, Jacqueline K. (1995) Structural Examination of Enantioselective Intercalation: ^1H NMR of Rh(en)_2phi^(3+) Isomers Bound to d(GTGCAC)_2 Biochemistry; Vol. 34; No. 46; https://resolver.caltech.edu/CaltechAUTHORS:20160405-140025577
Terbrueggen, Robert H.; Barton, Jacqueline K. (1995) Sequence-Specific DNA Binding by a Rhodium Complex: Recognition Based on Sequence-Dependent Twistability Biochemistry; Vol. 34; No. 26; https://resolver.caltech.edu/CaltechAUTHORS:20160405-140026640
Sardesai, Niranjan Y.; Lin, Susanne C. et al. (1995) Construction of Coordinatively Saturated Rhodium Complexes Containing Appended Peptides Bioconjugate Chemistry; Vol. 6; No. 3; https://resolver.caltech.edu/CaltechAUTHORS:20160405-133522969
Sitlani, Ayesha; Barton, Jacqueline K. (1994) Sequence-Specific Recognition of DNA by Phenanthrenequinone Diimine Complexes of Rhodium(III): Importance of Steric and van der Waals Interactions Biochemistry; Vol. 33; No. 40; https://resolver.caltech.edu/CaltechAUTHORS:20160406-085310442
Sardesai, Niranjan Y.; Zimmermann, Kaspar et al. (1994) DNA Recognition by Peptide Complexes of Rhodium(III): Example of a Glutamate Switch Journal of the American Chemical Society; Vol. 116; No. 17; https://resolver.caltech.edu/CaltechAUTHORS:20180601-153001625
Murphy, Catherine J.; Arkin, Michelle R. et al. (1994) Fast Photoinduced Electron Transfer through DNA Intercalation Proceedings of the National Academy of Sciences of the United States of America; Vol. 91; No. 12; https://resolver.caltech.edu/CaltechAUTHORS:MURpnas94
Campisi, Donna; Morii, Takashi et al. (1994) Correlations of Crystal Structures of DNA Oligonucleotides with Enantioselective Recognition by Rh(phen)_2phi^(3+): Probes of DNA Propeller Twisting in Solution Biochemistry; Vol. 33; No. 14; https://resolver.caltech.edu/CaltechAUTHORS:20160406-075128792
Turro, Claudia; Bossmann, Stefan H. et al. (1994) Ligand-Specific Charge Localization in the MLCT Excited State of Ru(bpy)_2(dpphen)^(2+) Monitored by Time-Resolved Resonance Raman Spectroscopy Inorganic Chemistry; Vol. 33; No. 7; https://resolver.caltech.edu/CaltechAUTHORS:20180413-144638081
Krotz, Achim H.; Hudson, Brian P. et al. (1993) [Assembly of DNA recognition elements on an octahedral rhodium intercalator: predictive recognition of 5'-TGCA-3' by Δ-[Rh[(R,R)-Me_2trien]phi]^(3+)](https://resolver.caltech.edu/CaltechAUTHORS:20180529-143627642 "Title links to perma link") Journal of the American Chemical Society; Vol. 115; No. 26; https://resolver.caltech.edu/CaltechAUTHORS:20180529-143627642
Sitlani, Ayesha; Dupureur, Cynthia M. et al. (1993) Enantiospecific palindromic recognition of 5'-d(CTCTAGAG)-3' by a novel rhodium intercalator: analogies to a DNA-binding protein Journal of the American Chemical Society; Vol. 115; No. 26; https://resolver.caltech.edu/CaltechAUTHORS:20180529-144212315
Krotz, Achim H.; Kuo, Louis Y. et al. (1993) Metallointercalators: syntheses, structures, and photochemical characterizations of phenanthrenequinone diimine complexes of rhodium(III) Inorganic Chemistry; Vol. 32; No. 26; https://resolver.caltech.edu/CaltechAUTHORS:20180601-135454004
Murphy, C. J.; Arkin, M. R. et al. (1993) Long-range photoinduced electron transfer through a DNA helix Science; Vol. 262; No. 5136; https://resolver.caltech.edu/CaltechAUTHORS:20150121-165643265
Lim, Ai Ching; Barton, Jacqueline K. (1993) Chemical Probing of tDNA^(Phe) with Transition Metal Complexes: A Structural Comparison of RNA and DNA Biochemistry; Vol. 32; No. 41; https://resolver.caltech.edu/CaltechAUTHORS:20160405-153102472
Lee, Inho; Barton, Jacqueline K. (1993) A Distinct Intron-DNA Structure in Simian Virus 40 T-Antigen and Adenovirus 2 E1A Genes Biochemistry; Vol. 32; No. 24; https://resolver.caltech.edu/CaltechAUTHORS:20160405-140026351
David, Sheila S.; Barton, Jacqueline K. (1993) NMR evidence for specific intercalation of Δ-rh(phen)_2phi^(3+) in [d(GTCGAC)_2] Journal of the American Chemical Society; Vol. 115; No. 7; https://resolver.caltech.edu/CaltechAUTHORS:20180501-151531707
Jenkins, Yonchu; Friedman, Alan E. et al. (1992) Characterization of dipyridophenazine complexes of ruthenium(II): The light switch effect as a function of nucleic acid sequence and conformation Biochemistry; Vol. 31; No. 44; https://resolver.caltech.edu/CaltechAUTHORS:20160406-091731528
Schaefer, William P.; Krotz, Achim H. et al. (1992) Metallointercalators: structure of rac-bis(ethylenediamine)(9,10-phenanthrenequinone diimine)rhodium(III) tribromide trihydrate Acta Crystallographica Section C; Vol. 48; No. 11; https://resolver.caltech.edu/CaltechAUTHORS:20160914-152612759
Hartshorn, Richard M.; Barton, Jacqueline K. (1992) Novel dipyridophenazine complexes of ruthenium(II): exploring luminescent reporters of DNA Journal of the American Chemical Society; Vol. 114; No. 15; https://resolver.caltech.edu/CaltechAUTHORS:20170905-104309030
Chow, Christine S.; Hartmann, Kevin M. et al. (1992) Delineation of Structural Domains in Eukaryotic 5S rRNA with a Rhodium Probe Biochemistry; Vol. 31; No. 13; https://resolver.caltech.edu/CaltechAUTHORS:20160406-093104747
Sitlani, Ayesha; Long, Eric C. et al. (1992) DNA photocleavage by phenanthrenequinone diimine complexes of rhodium(III): shape-selective recognition and reaction Journal of the American Chemical Society; Vol. 114; No. 7; https://resolver.caltech.edu/CaltechAUTHORS:20180724-152025087
Kim, Yun; Long, Eric C. et al. (1992) Imaging of oligonucleotide-metal complexes by scanning tunneling microscopy Langmuir; Vol. 8; No. 2; https://resolver.caltech.edu/CaltechAUTHORS:20180720-112834170
Chow, Christine S.; Behlen, Linda S. et al. (1992) Recognition of Tertiary Structure in tRNAs by Rh(phen)_2phi^(3+) a New Reagent for RNA Structure-Function Mapping Biochemistry; Vol. 31; No. 4; https://resolver.caltech.edu/CaltechAUTHORS:20160406-071104818
Huber, Paul W.; Morii, Takashi et al. (1991) Structural polymorphism in the major groove of a 5S RNA gene complements the zinc finger domains of transcription factor IIIA Proceedings of the National Academy of Sciences of the United States of America; Vol. 88; No. 23; https://resolver.caltech.edu/CaltechAUTHORS:HUBpnas91
Turro, Nicholas J.; Barton, Jacqueline K. et al. (1991) Molecular recognition and chemistry in restricted reaction spaces. Photophysics and photoinduced electron transfer on the surfaces of micelles, dendrimers, and DNA Accounts of Chemical Research; Vol. 24; No. 11; https://resolver.caltech.edu/CaltechAUTHORS:20170408-155617082
Orellana, Guillermo; Kirsch-De Mesmaeker, Andree et al. (1991) Photoinduced electron transfer quenching of excited Ru(II) polypyridyls bound to DNA: the role of the nucleic acid double helix Photochemistry and Photobiology; Vol. 54; No. 4; https://resolver.caltech.edu/CaltechAUTHORS:20160126-113442705
Friedman, Alan E.; Kumar, Challa V. et al. (1991) Luminescence of ruthenium(II) polypyridyls: evidence for intercalative binding to Z-DNA Nucleic Acids Research; Vol. 19; No. 10; https://resolver.caltech.edu/CaltechAUTHORS:20160406-134002391
Long, Eric C.; Barton, Jacqueline K. (1990) On demonstrating DNA intercalation Accounts of Chemical Research; Vol. 23; No. 9; https://resolver.caltech.edu/CaltechAUTHORS:20171108-084900678
Kirsch-De Mesmaeker, Andree; Orellana, Guillermo et al. (1990) Ligand-dependent interaction of ruthenium(II) polypyridyl complexes with DNA probed by emission spectroscopy Photochemistry and Photobiology; Vol. 52; No. 3; https://resolver.caltech.edu/CaltechAUTHORS:20160126-113616996
Friedman, Alan E.; Chambron, Jean Claude et al. (1990) A molecular light switch for DNA: Ru(bpy)_2(dppz)^(2+) Journal of the American Chemical Society; Vol. 112; No. 12; https://resolver.caltech.edu/CaltechAUTHORS:20180430-145302174
Rehmann, Jill P.; Barton, Jacqueline K. (1990) ^1H NMR Studies of Tris(phenanthroline) Metal Complexes Bound to Oligonucleotides: Characterization of Binding Modest Biochemistry; Vol. 29; No. 7; https://resolver.caltech.edu/CaltechAUTHORS:20160516-112833530
Rehmann, Jill P.; Barton, Jacqueline K. (1990) ^1H NMR Studies of Tris(phenanthroline) Metal Complexes Bound to Oligonucleotides: Structural Characterizations via Selective Paramagnetic Relaxation Biochemistry; Vol. 29; No. 7; https://resolver.caltech.edu/CaltechAUTHORS:20160516-112834153
Uchida, Kiyoshi; Pyle, Anna Marie et al. (1989) High resolution footprinting of EcoRI and distamycin with Rh(phi)_2(bpy)^(3+), a new photofootprinting reagent Nucleic Acids Research; Vol. 17; No. 24; https://resolver.caltech.edu/CaltechAUTHORS:20160513-121954121
Purugganan, Michael D.; Kumar, Challa V. et al. (1988) Accelerated Electron Transfer Between Metal Complexes Mediated by DNA Science; Vol. 241; No. 4873; https://resolver.caltech.edu/CaltechAUTHORS:20160513-104502311
Chapnick, Lowell B.; Chasin, Lawrence A. et al. (1988) In vivo photoreaction of a chiral cobalt complex: DNA cleavage by Co(DIP)_3^(3+) in mammalian cells Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis; Vol. 201; No. 1; https://resolver.caltech.edu/CaltechAUTHORS:20160513-104524679
Mei, Houng-Yau; Barton, Jacqueline K. (1988) Tris(tetramethylphenanthroline)ruthenium(II): A chiral probe that cleaves A-DNA conformations Proceedings of the National Academy of Sciences of the United States of America; Vol. 85; No. 5; https://resolver.caltech.edu/CaltechAUTHORS:MEIpnas88
Kirshenbaum, Mindy R.; Tribolet, Roger et al. (1988) Rh(DIP)_3^(3+): a shape-selective metal complex which targets cruciforms Nucleic Acids Research; Vol. 16; No. 16; https://resolver.caltech.edu/CaltechAUTHORS:20160513-123130441
Müller, Barbara C.; Raphael, Adrienne L. et al. (1987) Evidence for altered DNA conformations in the simian virus 40 genome: Site-specific DNA cleavage by the chiral complex Lambda-tris(4,7-diphenyl-1,10-phenanthroline)cobalt(III) Proceedings of the National Academy of Sciences of the United States of America; Vol. 84; No. 7; https://resolver.caltech.edu/CaltechAUTHORS:MULpnas87
Barton, Jacqueline K. (1986) Metals and DNA: molecular left-handed complements Science; Vol. 233; No. 4765; https://resolver.caltech.edu/CaltechAUTHORS:20160513-113952809
Barton, Jacqueline K.; Paranawithana, Shanthi R. (1986) Restriction Endonuclease EcoRI Alters the Enantiomeric Preference of Chiral Metallointercalators for DNA: An Illustration of a Protein-Induced DNA Conformational Change Biochemistry; Vol. 25; No. 8; https://resolver.caltech.edu/CaltechAUTHORS:20160516-132218229
Barton, Jacqueline K.; Raphael, Adrienne L. (1985) Site-Specific Cleavage of Left-Handed DNA in pBR322 by Lambda-tris(diphenylphenanthroline)cobalt(III) Proceedings of the National Academy of Sciences of the United States of America; Vol. 82; No. 19; https://resolver.caltech.edu/CaltechAUTHORS:BARpnas85
Barton, Jacqueline K.; Basile, Lena A. et al. (1984) Chiral probes for the handedness of DNA helices: Enantiomers of tris(4, 7-diphenylphenanthroline)ruthenium(II) Proceedings of the National Academy of Sciences of the United States of America; Vol. 81; No. 7; https://resolver.caltech.edu/CaltechAUTHORS:BARpnas84
Barton, Jacqueline K.; Nowick, James S. (1984) Application of Chiral Lanthanide-induced Shift Reagents to Optically Active Cations: the Use of Tris[3-(trifluoromethylhydroxymethylene)-( + )-camphorato]europium(III) to Determine the Enantiomeric Purity of Tris(phenanthroline)ruthenium(II) Dichloride Journal of the Chemical Society. Chemical Communications; Vol. 1984; No. 24; https://resolver.caltech.edu/CaltechAUTHORS:20120629-111938166
Barton, Jacqueline K. (1983) Tris (phenanthroline) Metal Complexes: Probes for DNA Helicity Journal of Biomolecular Structure and Dynamics; Vol. 1; No. 3; https://resolver.caltech.edu/CaltechAUTHORS:20160126-115600120
Tomasz, Maria; Barton, Jacqueline K. et al. (1983) Lack of Z-DNA Conformation in Mitomycin-Modified Polynucleotides Having Inverted Circular Dichroism Proceedings of the National Academy of Sciences of the United States of America; Vol. 80; No. 10; https://resolver.caltech.edu/CaltechAUTHORS:TOMpnas83
Barton, Jacqueline K.; Basile, Lena A. et al. (1982) The presence of zinc in the restriction enzyme Eco RI Journal of Biological Chemistry; Vol. 257; No. 14; https://resolver.caltech.edu/CaltechAUTHORS:20160520-112839737
Barton, J. K.; den Hollander, J. A. et al. (1982) ^(13)C nuclear magnetic resonance study of trehalose mobilization in yeast spores Journal of Bacteriology; Vol. 151; No. 1; https://resolver.caltech.edu/CaltechAUTHORS:BARjbact82
Barton, J. K.; den Hollander, J. A. et al. (1980) Measurement of the Internal pH of Yeast Spores by 31P Nuclear Magnetic Resonance Proceedings of the National Academy of Sciences of the United States of America; Vol. 77; No. 5; https://resolver.caltech.edu/CaltechAUTHORS:BARpnas80
Barton, Jacqueline K.; Caravana, Carl et al. (1979) Chemical and spectroscopic characterization of cis-diammineplatinum α-pyridone blue in aqueous solution. Comparison with other platinum blues Journal of the American Chemical Society; Vol. 101; No. 24; https://resolver.caltech.edu/CaltechAUTHORS:20171103-154149592
Barton, Jacqueline K.; Lippard, Stephen J. (1979) Cooperative binding of a platinum metallointercalation reagent to poly(A)•poly(U) Biochemistry; Vol. 18; No. 12; https://resolver.caltech.edu/CaltechAUTHORS:20160126-164902771
Cohen, Gary L.; Bauer, William R. et al. (1979) Binding of cis- and trans-dichlorodiammineplatinum(II) to DNA: evidence for unwinding and shortening of the double helix Science; Vol. 203; No. 4384; https://resolver.caltech.edu/CaltechAUTHORS:20160126-165802210
Barton, Jacqueline K.; Lippard, Stephen J. (1978) A crystalline platinum blue: its molecular structure, chemical reactivity, and possible relevance to the mode of action of antitumor platinum drugs Annals of the New York Academy of Sciences; Vol. 313; https://resolver.caltech.edu/CaltechAUTHORS:20160126-164221837
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