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Gözde Demirer

Research Summary
Nanotechnology, Nano-bio interactions, Plant genome editing, Synthetic biology and bioengineering, Sustainable agriculture
Profile

Assistant: Irina Meininger

Gözde was born and raised in Istanbul, Turkey and received her B.S. in Chemical and Biological Engineering from Koc University in 2015. Gözde completed her Chemical Engineering Ph.D. at UC Berkeley with Prof. Markita Landry in 2020. During her Ph.D. studies, she developed nanotechnologies for plant genetic engineering. For her postdoctoral work, Gözde joined Prof. Siobhan Brady's lab at UC Davis, where she studies nutrient use efficiency of tomato and develops high-throughput functional genomics tools to study transcriptional regulation in crops. 

The Demirer lab will work on bioengineering of plants and rhizosphere for food security, sustainability, and environmental remediation using novel nanotechnology and synthetic biology approaches.

Twitter: @Demirer_GozdeS

Publications

For a complete publications list, see https://scholar.google.com/citations?user=WAhEY-QAAAAJ&hl=en

Toolboxes for Plant Systems Biology Research. Jihyun Park, Gozde S. Demirer, Lily S Cheung, Current Opinion in Biotechnology, 2022.https://doi.org/10.1016/j.copbio.2022.102692

Nanoparticle cellular internalization is not required for RNA delivery to mature plant leaves. Huan Zhang, Natalie S Goh, Jeffrey W Wang, Rebecca L Pinals, Eduardo González-Grandío, Gozde S Demirer, Salwan Butrus, Sirine C Fakra, Antonio Del Rio Flores, Rui Zhai, Bin Zhao, So-Jung Park, Markita P Landry, Nature Nanotechnology, 2022.https://doi.org/10.1038/s41565-021-01018-8

A Ratiometric Dual Color Luciferase Reporter for Fast Characterization of Transcriptional Regulatory Elements in Plants. Eduardo González-Grandío, Gozde S Demirer, Wenhe Ma, Siobhan Brady, Markita P Landry, ACS Synthetic Biology, 2021.https://doi.org/10.1021/acssynbio.1c00248

Carbon nanotube biocompatibility in plants is determined by their surface chemistry. Eduardo González-Grandío, Gozde S. Demirer, Christopher T Jackson, Darwin Yang, Sophia Ebert, Kian Molawi, Harald Keller, Markita P Landry, Journal of Nanobiotechnology, 2021.https://doi.org/10.1186/s12951-021-01178-8

Nanotechnology to advance CRISPR/Cas genetic engineering of plants. Gozde S Demirer, Tallyta Silva, Christopher Jackson, Jason Thomas, David Ehrhardt, Seung Y. Rhee, Jenny C. Mortimer and Markita P. Landry, Nature Nanotechnology (accepted), 2021. https://doi.org/10.1038/s41565-021-00854-y

Efficient Transient Gene Knock-down in Tobacco Plants Using Carbon Nanocarriers. Gozde S Demirer and Markita P Landry, bio-protocol, 2021. https://bio-protocol.org/e3897

Engineering DNA nanostructures for siRNA delivery in plants. Huan Zhang, Honglu Zhang, Gozde S Demirer, Eduardo González-Grandío, Chunhai Fan, Markita P Landry, Nature Protocols, 2020. https://doi.org/10.1038/s41596-020-0370-0

Carbon nanocarriers deliver siRNA to intact plant cells for efficient gene knockdown. Gozde S Demirer, Huan Zhang, Natalie S Goh, Rebecca L Pinals, Roger Chang, Markita P Landry, Science Advances, 2020. https://doi.org/10.1126/sciadv.aaz0495

Carbon nanotube–mediated DNA delivery without transgene integration in intact plants. Gozde S Demirer, Huan Zhang, Natalie S Goh, Eduardo González-Grandío, Markita P Landry, Nature Protocols, 2019. https://doi.org/10.1038/s41596-019-0208-9

High aspect ratio nanomaterials enable delivery of functional genetic material without DNA integration in mature plants. Gozde S Demirer, Huan Zhang, Juliana Matos, Natalie Goh, Francis Cunningham, Younghun Sung, Roger Chang, Abhishek Aditham, Linda Chio, Myeong-Je Cho, Brian Staskawicz, Markita P Landry, Nature Nanotechnology, 2019. https://doi.org/10.1038/s41565-019-0382-5

DNA nanostructures coordinate gene silencing in mature plants. Huan Zhang*, Gozde S Demirer*, Honglu Zhang, Tianzheng Ye, Natalie S Goh, Abhishek J Aditham, Francis J Cunningham, Chunhai Fan, Markita P Landry, PNAS, 2019. https://doi.org/10.1073/pnas.1818290116

Nanoparticle-mediated delivery towards advancing plant genetic engineering. Francis J Cunningham*, Natalie S Goh*, Gozde S Demirer, Juliana L Matos, Markita P Landry, Trends in Biotechnology, 2018. https://doi.org/10.1016/j.tibtech.2018.03.009

Delivering genes to plants. Gozde S Demirer and Markita P Landry, Chemical Engineering Progress, 2017. https://escholarship.org/uc/item/2hp0j2g2

2025-26
ChE 101. Chemical Reaction Engineering. 9 units (3-0-6); second term, 2025-26. Prerequisites: ChE 62, ChE 63 ab, ChE 103 a or instructor's permission. Elements of chemical kinetics and chemically reacting systems. Chemical reactor analysis. Homogeneous and heterogeneous catalysis. Biological and environmental reaction engineering. Enzyme kinetics. Lectures include case studies from real world applications of various chemical engineering subfields. Problem sets contain computational approaches to chemical kinetics and reactor design.
Instructor: Demirer
ChE/Ch/BE 130. Biomolecular Engineering Laboratory. 9 units (0-6-3); third term, 2025-26. Prerequisites: BE/ChE 163 or instructor's permission. Design, construction, and characterization of engineered biological systems. Students propose and execute research projects in biomolecular engineering, synthetic biology, and genetic engineering fields. Projects will cover a broad range of molecular and cell biology, and genetics and genomics lab techniques.
Instructor: Demirer
2022-23
ChE 101. Chemical Reaction Engineering. 9 units (3-0-6); second term, 2022-23. Prerequisites: ChE 62, ChE 63 ab, ChE 103 a or instructor's permission. Elements of chemical kinetics and chemically reacting systems. Homogeneous and heterogeneous catalysis. Chemical reactor analysis.
Instructor: Demirer