Peter B. Dervan

Bren Professor of Chemistry, Emeritus

B.S., Boston College, 1967; Ph.D., Yale University, 1972; Assistant Professor, Caltech, 1973-79; Associate Professor, 1979-82; Professor, 1982-88; Bren Professor, 1988-. Chair, Division of Chemistry and Chemical Engineering, 1994-99.

Email: [email protected]

Phone: 626-395-6002

Office: Crellin Laboratory 351

Mail Code: MC 164-30 CR

Research Summary

Organic, Physical Organic, and Chemical Biology

Profile

Assistant: Aracely Sustaita

Professor Dervan's research program addresses a wide range of fundamental problems at the interface of organic chemistry and biology. Elucidating the chemical principles for the molecular recognition of DNA by small molecules and their use in biology, in particular gene modulation and DNA detection, are unifying themes.

For a complete publications list, see feeds.library.caltech.edu

Finn, Paul B.; Bhimsaria, Devesh et al. (2020) Single position substitution of hairpin pyrrole-imidazole polyamides imparts distinct DNA-binding profiles across the human genome

Kurmis, Alexis A.; Dervan, Peter B. (2019) Sequence specific suppression of androgen receptor–DNA binding in vivo by a Py-Im polyamide

Dervan, Peter B. (2019) A Personal Perspective on Chemical Biology: Before the Beginning

Diaz-Perez, Silvia; Kane, Nathanael et al. (2018) Interference with DNA repair after ionizing radiation by a pyrrole-imidazole polyamide

Dervan, Peter B.; Kurmis, Alexis A. et al. (2018) Molecular Recognition of DNA by Py–Im Polyamides: From Discovery to Oncology In: DNA-targeting Molecules as Therapeutic Agents

Publications