Frances H. Arnold

Dick and Barbara Dickinson Professor of Chemical Engineering, Bioengineering and Biochemistry; Director, Donna and Benjamin M. Rosen Bioengineering Center
B.S., Princeton University, 1979; Ph.D., University of California, 1985. Visiting Associate, Caltech, 1986; Assistant Professor of Chemical Engineering, 1987-92; Associate Professor, 1992-96; Professor, 1996-99; Professor of Chemical Engineering and Biochemistry, 1999-2000. Dickinson Professor, 2000-; Director, Rosen Bioengineering Center, 2013-.

Dual Affiliation with Division of Engineering and Applied Science

Assistant: Cheryl Nakashima

Research in the Arnold group focuses on evolutionary protein design methods (1,2) and using the results of laboratory evolution experiments to elucidate principles of biological design.

We generate novel and useful enzymes and organisms for applications in medicine, neurobiology, chemical synthesis and alternative energy. We also construct entire synthetic families of enzymes and other proteins in order to study structure-function relationships free from constraints of natural selection.

This research requires contributions from many disciplines, including chemistry, bioengineering, biochemistry, molecular biology, microbiology, chemical engineering, chemistry and applied physics.

Selected Awards: 
National Inventors Hall of Fame (2014); Doctorate honoris causa, Stockholm University (2013); ENI Prize in Renewable and Nonconventional Energy (2013); E. Merck Lectures in Chemistry (2013); National Medal of Technology and Innovation (2011); Charles Stark Draper Prize (2011); American Academy of Arts and Sciences (2011); Fellow, American Association for the Advancement of Science (2010); Fellow, American Academy of Microbiology (2009); National Academy of Sciences (2008); Linnaeus Lecturer, Uppsala University (2008);Cruickshank Lecturer, Gordon Research Conferences (2008);Enzyme Engineering Award (2007); FASEB Excellence in Science Award (2007); Food, Pharmaceuticals, and Bioengineering Division Award, AIChE (2005); Francis P. Garvan-John M. Olin Medal, ACS (2005); Institute of Medicine of the National Academies (2004); Carothers Award of the ACS Delaware Division (2003); David Perlman Lecture Award, ACS, Biochemical Technology (2003); Sir Robert Price Lecturer, CSIRO, Melbourne (2003); Fellow, AIMBE (2001); National Academy of Engineering (2000); Professional Progress Award of the AIChE (2000).
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