BMB Faculty Research

(BMB is an interdisciplinary option whose faculty are distributed within the Division of Biology & Biological Engineering and the Division of Chemistry & Chemical Engineering)


BMB Faculty


BMB Research Focus

Alexei A. Aravin

Professor of Biology

Small RNAs and regulation of gene expression

Frances H. Arnold

Linus Pauling Professor of Chemical Engineering, Bioengineering and Biochemistry; Director, Donna and Benjamin M. Rosen Bioengineering Center


In vitro molecular evolution, protein engineering

David Baltimore

President Emeritus; Robert Andrews Millikan Professor of Biology

Transcription factors and intracellular signaling molecules

Jacqueline K. Barton

John G. Kirkwood and Arthur A. Noyes Professor of Chemistry; Norman Davidson Leadership Chair, Division of Chemistry and Chemical Engineering


Chemistry of nucleic acids, design of metal complexes to probe DNA

Pamela J. Bjorkman

Centennial Professor of Biology


Structures of proteins mediating the immune response; protein crystallography

Judith L. Campbell

Professor of Chemistry and Biology

Mechanisms of regulation of DNA replication, repair, and cell cycle progression

David Chan

Professor of Biology

Mitochondrial dynamics in cell physiology and disease

William "Bil" Clemons

Professor of Biochemistry


Studies of protein synthesis and translocation using macromolecular crystallography

Peter B. Dervan

Bren Professor of Chemistry


Bioorganic chemistry of proteins and nucleic acids

Raymond Deshaies

Visiting Associate in Biology and Biological Engineering


Homeostasis and the Ubiquitin-Proteasome System in Health and Disease

Dennis A. Dougherty

George Grant Hoag Professor of Chemistry


Chemical-scale studies of ion channel proteins

William G. Dunphy

Grace C. Steele Professor of Biology

Regulation of the Cell Cycle and Maintenance of Genomic Integrity

Michael Elowitz

Professor of Biology and Bioengineering; Investigator, Howard Hughes Medical Institute; Executive Officer for Biological Engineering


Biophysics; biocomputing; gene regulation networks and variation in living cells

William A. Goddard III

Charles and Mary Ferkel Professor of Chemistry, Materials Science, and Applied Physics; Director of Materials and Process Simulation Center


Protein folding, drugs binding to proteins and DNA (theory)

Lea Goentoro

Professor of Biology

Physics, dynamics, and molecular mechanisms of cell signaling, gene regulation, and regeneration

Viviana Gradinaru

Professor of Biology and Biological Engineering, Investigator, Heritage Medical Research Institute; Director, Center for Molecular and Cellular Neuroscience


Focuses on control of brain function and behavior

Harry B. Gray

Arnold O. Beckman Professor of Chemistry; Founding Director, Beckman Institute


Electron transfer in biological molecules; inorganic photochemistry

Mitchell Guttman

Assistant Professor of Biology; Investigator, Heritage Medical Research Institute


Mechanisms of large non-coding RNA mediated regulation of gene expression and cell state

Bruce A. Hay

Professor of Biology


Molecular genetics of cell death

Elizabeth Hong

Clare Boothe Luce Assistant Professor of Neuroscience


Andre Hoelz

Professor of Biochemistry


Structure-function studies of the nuclear pore complex and the histone-modifying machinery; X-ray crystallography

Linda Hsieh-Wilson

Arthur and Marian Hanisch Memorial Professor of Chemistry


Bioorganic chemistry; protein structure and function; signal transduction; neurobiology

Rustem F. Ismagilov

John W. and Herberta M. Miles Professor of Chemistry and Chemical Engineering


Global Health; Microbial communities and biophysics of the gut microbiome; Diagnostics and antimicrobial susceptibility testing; Microfluidics and single molecule and single cell analysis;   Complex Networks of reactions, cells and organisms

Grant Jensen

Professor of Biophysics and Biology; Investigator, Howard Hughes Medical Institute


Structure of large protein machines and their arrangement within cells by cryoelectron microscopy

Mary B. Kennedy

The Allen and Lenabelle Davis Professor of Biology


Molecular structure and regulation of CNS synapses

Jared R. Leadbetter

Professor of Environmental Microbiology


Novel microbes with novel metabolic activities

Henry A. Lester

Professor of Biology


Molecular structure and regulation of CNS synapses

Stephen L. Mayo

Bren Professor of Biology and Chemistry; William K. Bowes Jr. Leadership Chair, Division of Biology and Biological Engineering


Protein design, structure, and stability; computer simulation techniques

Sarkis Mazmanian

Luis B. and Nelly Soux Professor of Microbiology; Investigator, Heritage Medical Research Institute


Markus Meister

Anne P. and Benjamin F. Biaggini Professor of Biological Sciences; Executive Officer for Neurobiology

Structure and function of neural circuits

Elliot Meyerowitz

George W. Beadle Professor of Biology; Investigator, Howard Hughes Medical Institute

Plant biology, plant biotechnology

Thomas Miller

Professor of Chemistry


Theory and simulation of chemical, biochemical, and soft matter systems

Richard M. Murray

Thomas E. and Doris Everhart Professor of Control and Dynamical Systems and Bioengineering


Analysis and design of biomolecular feedback systems

Dianne K. Newman

Gordon M. Binder/Amgen Professor of Biology and Geobiology; Allen V. C. Davis and Lenabelle Davis Leadership Chair, Center for Environmental Microbial Interactions; Executive Officer for Molecular Biology


Studies of microbial metabolism (respiration, photosynthesis, non-growth metabolism) using Pseudomonas aeruginosa and Rhodopseudomonas palustris as model systems; studies of the biological function of hopanoids, a class of lipids whose molecular fossils are retained in ancient rocks

Alison E. Ondrus

Assistant Professor of Chemistry


Metabolite signaling in development and oncogenesis

Carl S. Parker

Professor of Biochemistry


Transcriptional initiation and the control of gene expression

Joseph Parker

Assistant Professor of Biology and Biological Engineering



Rob Phillips

Fred and Nancy Morris Professor of Biophysics, Biology, and Physics


Physics of macromolecules and their assemblies

Niles A. Pierce

Professor of Applied and Computational Mathematics and Bioengineering


 Engineering small conditional DNAs and RNAs for signal transduction in vitro, in situ, and in vivo; computational algorithms for the analysis and design of nucleic acid systems; programmable molecular instruments for readout and regulation of cell state

David Prober

Professor of Biology



Douglas C. Rees

Roscoe Gilkey Dickinson Professor of Chemistry; Investigator, Howard Hughes Medical Institute; Dean of Graduate Studies


Macromolecular crystallography; structure and function of proteins and nucleic acids

Ellen V. Rothenberg

Albert Billings Ruddock Professor of Biology

 Control of gene expression in lymphocyte development

Paul Rothmund

Research Professor of Bioengineering, Computing and Mathematical Sciences, and Computation and Neural Systems

Artificial DNA and RNA nanostructures as templates for technological and biological devices

Shu-ou Shan

Professor of Chemistry; Executive Officer for Biochemistry and Molecular Biophysics


 Macromolecular machines; protein sorting and localization; molecular recognition and regulation of novel GTPases

Mikhail Shapiro

Assistant Professor of Chemical Engineering

Molecular engineering for imaging and remote control of cellular function in vivo

Angelike Stathopoulos

Professor of Biology


 Whole genome approach to studying gastrulation in Drosophila

Paul W. Sternberg

Bren Professor of Biology


Signal transduction and transcription networks in C. elegans

Matt Thomson

Assistant Professor of Computational Biology


Applying mathematical models to engineer and control cell behavior

David Tirrell

Provost; Ross McCollum-William H. Corcoran Professor of Chemistry and Chemical Engineering; Carl and Shirley Larson Provostial Chair


 Biocatalysis; biomaterials; polymer science; protein engineering; macromolecular chemistry

David Van Valen

Research Assistant Professor of Biology and Biological Engineering



Alexander Varshavsky

Howard and Gwen Laurie Smits Professor of Cell Biology

 Intracellular protein degradation and the N-end rule

Rebecca Voorhees

Assistant Professor of Biology and Biological Engineering; Investigator, Heritage Medical Research Institute


Structural and functional studies of protein biosynthesis and quality control; cryo-electron microscopy

Zhen-Gang Wang

Dick and Barbara Dickinson Professor of Chemical Engineering

Theoretical and computational study of soft matter, macromolecular and biophysics systems

Erik Winfree

Professor of Computer Science, Computation and Neural Systems, and Bioengineering


Nucleic acid engineering and molecular programming

Barbara J. Wold

Bren Professor of Molecular Biology


Regulation of muscle differentiation

Kai G. Zinn

Howard and Gwen Laurie Smits Professor of Biology


Molecular mechanisms of nervous system development